ID A0A1I7ZFT8_9BILA Unreviewed; 396 AA.
AC A0A1I7ZFT8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Neur_chan_LBD domain-containing protein {ECO:0000313|WBParaSite:L893_g25756.t2};
OS Steinernema glaseri.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Steinernematidae;
OC Steinernema.
OX NCBI_TaxID=37863 {ECO:0000313|Proteomes:UP000095287, ECO:0000313|WBParaSite:L893_g25756.t2};
RN [1] {ECO:0000313|WBParaSite:L893_g25756.t2}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR AlphaFoldDB; A0A1I7ZFT8; -.
DR WBParaSite; L893_g25756.t2; L893_g25756.t2; L893_g25756.
DR Proteomes; UP000095287; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR CDD; cd18987; LGIC_ECD_anion; 1.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 1.
DR InterPro; IPR006028; GABAA/Glycine_rcpt.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR006201; Neur_channel.
DR InterPro; IPR038050; Neuro_actylchol_rec.
DR PANTHER; PTHR18945:SF767; NEUR_CHAN_LBD DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR Pfam; PF02931; Neur_chan_LBD; 1.
DR PRINTS; PR00253; GABAARECEPTR.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..396
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009313401"
FT TRANSMEM 246..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..202
FT /note="Neurotransmitter-gated ion-channel ligand-binding"
FT /evidence="ECO:0000259|Pfam:PF02931"
SQ SEQUENCE 396 AA; 44618 MW; 8BA2F69674E4DE7A CRC64;
MRLISRIIFI CISCLAAVSQ AQNKAIRSRQ IGTEGQIIAK VFSNYDKDTR PPVRENADHS
SIVVITSIYI NSVKWETNSA EVDLYLREQW MDSRLKYDVD VREQIQEVMV PGNRKIWKPD
TYFSNGKELA VEGKQSAVIE PSGYVRSSEG RTVIVPIEYQ SKFPFLNALS FTLRLSSYNY
ALEDVAYLWA NSPPNAVALE VSGQLLNSEY SFQEAVAGDC VGNYSVGVYS CIDVVVSFET
SCAKTLLSVF LPTILLVIAS FLHFWIHGSW SVPRSFSAGF PFLILASLFV FAPNSTFFVS
PGVRVWTIFC LIITFFSFLE YFLVICCGIR RTVKYTNGIA TQEQNALTSA QETVELAYNT
KCANFRDNNG LDIISRVLFP LVFIVFIIVY LVLYLI
//
