ID   A0A1I7ZU11_9BILA        Unreviewed;       526 AA.
AC   A0A1I7ZU11;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Nuclear receptor domain-containing protein {ECO:0000313|WBParaSite:L893_g29555.t1};
OS   Steinernema glaseri.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Steinernematidae;
OC   Steinernema.
OX   NCBI_TaxID=37863 {ECO:0000313|Proteomes:UP000095287, ECO:0000313|WBParaSite:L893_g29555.t1};
RN   [1] {ECO:0000313|WBParaSite:L893_g29555.t1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- FUNCTION: Orphan nuclear receptor. {ECO:0000256|ARBA:ARBA00037512}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC   -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC       {ECO:0000256|ARBA:ARBA00005993, ECO:0000256|RuleBase:RU004334}.
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DR   AlphaFoldDB; A0A1I7ZU11; -.
DR   WBParaSite; L893_g29555.t1; L893_g29555.t1; L893_g29555.
DR   Proteomes; UP000095287; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd06960; NR_DBD_HNF4A; 1.
DR   CDD; cd06157; NR_LBD; 1.
DR   Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR   Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR   InterPro; IPR049636; HNF4-like_DBD.
DR   InterPro; IPR035500; NHR-like_dom_sf.
DR   InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR   InterPro; IPR001628; Znf_hrmn_rcpt.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   PANTHER; PTHR47519; NUCLEAR HORMONE RECEPTOR FAMILY MEMBER NHR-31-RELATED; 1.
DR   PANTHER; PTHR47519:SF5; NUCLEAR RECEPTOR DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   Pfam; PF00105; zf-C4; 1.
DR   PRINTS; PR00047; STROIDFINGER.
DR   SMART; SM00430; HOLI; 1.
DR   SMART; SM00399; ZnF_C4; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR   PROSITE; PS51843; NR_LBD; 1.
DR   PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR   PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU004334};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU004334};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU004334};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT   DOMAIN          95..170
FT                   /note="Nuclear receptor"
FT                   /evidence="ECO:0000259|PROSITE:PS51030"
FT   DOMAIN          251..524
FT                   /note="NR LBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51843"
FT   REGION          166..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        166..180
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..208
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        224..245
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   526 AA;  57572 MW;  1B913780A658318A CRC64;
     MSQPVSSDAA TLVFANLANN VAAIMRGGSP GSAMTNPYLL AAASNAVTPP GTTYLSPVAG
     SCSPTLPTAH YSIDSILKAE EAEELAKMQN GFDEPSICSV CRDEASGRHY GVIACFGCKG
     FFRRTVRAGK HYTCRYEQKC RIDKAGRNVC RSCRFQKCLE VGMEPDAIRP DRDKTGRQKN
     PRRSATNGYM GSHDENQKKM STSSLLGDLP NVHHHDTAES SDDGRASSTD NATVDGRSAS
     SDESSGHSKI GDENIISTLI EIEGICNTLS DQMSGIRPNL VPLSDAVLRP VLIGPRTPLD
     YSGRNGIASY EQYNEALRRL MVLTLDYANT LKPIADFMPE EKACLVRTCL PSFTLLMTAY
     RSAVHGEEDQ ILLPNGFMFS RDSSMFKENS AVDDKRRTLL ETRIRVAKKN ILDQVVQQIR
     RYALTEAEYA ALKAIIALDP STPKISEKTA HLLSVARNSV QNALYVHLSN KLPPAQATYR
     FGNLLLLIAS VSKMGAAVLN VMQFCRDLQL EIDPVIDEIL FSDDSL
//