ID A0A1I8A165_9BILA Unreviewed; 1595 AA.
AC A0A1I8A165;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=UDENN domain-containing protein {ECO:0000313|WBParaSite:L893_g31821.t1};
OS Steinernema glaseri.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Steinernematidae;
OC Steinernema.
OX NCBI_TaxID=37863 {ECO:0000313|Proteomes:UP000095287, ECO:0000313|WBParaSite:L893_g31821.t1};
RN [1] {ECO:0000313|WBParaSite:L893_g31821.t1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RAB6IP1 family.
CC {ECO:0000256|ARBA:ARBA00006664}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR WBParaSite; L893_g31821.t1; L893_g31821.t1; L893_g31821.
DR Proteomes; UP000095287; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR CDD; cd17678; RUN2_DENND5; 1.
DR Gene3D; 1.20.58.900; -; 3.
DR Gene3D; 3.30.450.200; -; 1.
DR Gene3D; 3.40.50.11500; -; 2.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR047278; DEN5A/B.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR46070; PINSTRIPE, ISOFORM A; 1.
DR PANTHER; PTHR46070:SF1; PINSTRIPE, ISOFORM A; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 2.
DR Pfam; PF01477; PLAT; 1.
DR Pfam; PF02759; RUN; 2.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00593; RUN; 2.
DR SMART; SM00800; uDENN; 1.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR SUPFAM; SSF140741; RUN domain-like; 2.
DR PROSITE; PS50211; DENN; 1.
DR PROSITE; PS50095; PLAT; 1.
DR PROSITE; PS50826; RUN; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 49..726
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT DOMAIN 906..1209
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT DOMAIN 1214..1325
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1438..1591
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT REGION 170..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 829..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1335..1409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..549
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..586
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 836..857
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1339..1409
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1595 AA; 179362 MW; 58AD0EA1F267A31E CRC64;
MASSSLVDGS SANPESDLTL VDYFVVVGLD RDVGLTVDNS CDVSAELSSV QCRNSRPPME
RSYVSKVLSH FPEVRKSLPF SHEIVSLCMP KGLRFYTEKD VPKPAIHTFA NIREDGSRVN
GCALIFYETI LGKRSKLLRS KEVRDLNICE QMSLLHTEHV RELTAMEKHS DRVHHPPGTV
SGGNHTLPRG SRKNRSKRIS YYDVGCNQLY MSKCICLLTR IPIVGACENM LNSIYSMVCS
NSQPPPFALE SYIYWMLNEV PLPAPGSTLK VNLNSYELVL QRPGLRELPF FDYSMRQLFD
LVTVEKFLRL FSCFLLEHQI LLCSRSLQRL MLVAESLCVL AFPFRWQLAY VPILPYSQLK
FIEAPVPYVM GLCYEDCIPE QIYQVGDSEK LLPKITFDFA FVKSNRRILL ELMCSXXXXA
LQRLMLVAES LCVLAFPFRW QLAYVPILPY SQLKFIEAPV PYVMGLCYED CIPEQIYQSN
VCVMDIDTGE LDLPEDVPPL PQAKHLATEI TNLLNRAQAE SNSEVKMRPK KSSGLSTRKK
DEWSSKRMSR SFDDHAMGSV LNTAPRSAKV DFEQDDSDKE KDSPPILNDA WKMSETLARV
QAIARRAGVS VEMDSIEQEI HSNDSFMNSP TCKAYFKDMK LNNAIREVVL NVFVCLLYSY
DNFMIGGGMF EDSESYFANR DSVANFDKAS FLSDQPDSHL SFLAAFLETQ MFASVIDAKI
LSQWETPDEN LVIFEDRVER LRQKLGSAMV RTPTYETATA TAETDDLIVK REEAFDYIVP
KPHHIAGAVP DTYCGIFPEL NAAILEGSQF CSPVPSPWKQ RHRRLRPKKF DSGNFLNGTG
GGSGNATNRR STYGMGDTPE QIAKQNWKFV EQLLKETKGK TKRMLVEKMG KEAVQLGHVD
PSVTGIEENT LVASFCDLLE RIWAHGLFKK QGKSALWSHV LLHQEFEKTD AKAPLMTASL
SPAASQSTKI GFSIEDVEDD LENKEMDSTS NMGKLSEIVQ NIQKELKIEG DEGEDAPAWS
RSILRAANFI CDKISSASTN SSVLGPALSS AMIGRSQSFQ RAPNQKLTKA NSVSDFTPHW
TGSSDNVAAA ANSVEFARPE RKRSLSRPRS PDPRMALEPL PNHIAYDLKN VLRMTEIKTE
IGFARAFVRL ALERKLLHKH LKNILSRQQI LQKLYKRYAF LRCDEEKEQF LYHILSLNAA
DFNCFTNTFP RTKMQYEILI VTGNTKHLSS AGVWILLAGS LNSTPIIPLP SGSLQFTFDH
MNLGVLSTLR IGHDREKIEK YGTPPKWFLD YVIVRNQITS QTYRFNCGRW FGKGVDDGSL
ERLLVAECLP RPDPEADSPV SAFQTSGYGS SNGSSCQTTS SSSKGGSRSR ASSRVRSPSA
GRSSEAGQGS KTSISSEAGQ GSKTKTRTAE LQHLLGASVN ALVQHFYAAE KGGDRQLTQL
LCGERGLVSC LEQVFALGRY DAHWTNRLFK QPYPWDYIEK VSGWFVNLFH CGEYRKLTRE
QRALIVHSCN LVQKISTNNS VGKDGKFHAF ILLTLRDHIL SGLLPLMAWT PVTSQMYDET
SFLRNPTHLS YLSKLLNSLN EFQFKLEKSL TYGIE
//
