ID A0A1I8AC23_9BILA Unreviewed; 1468 AA.
AC A0A1I8AC23;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Cubilin {ECO:0000313|WBParaSite:L893_g4218.t1};
OS Steinernema glaseri.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Steinernematidae;
OC Steinernema.
OX NCBI_TaxID=37863 {ECO:0000313|Proteomes:UP000095287, ECO:0000313|WBParaSite:L893_g4218.t1};
RN [1] {ECO:0000313|WBParaSite:L893_g4218.t1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR WBParaSite; L893_g4218.t1; L893_g4218.t1; L893_g4218.
DR Proteomes; UP000095287; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00041; CUB; 4.
DR CDD; cd00054; EGF_CA; 6.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 5.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR47761:SF1; C-TYPE LECTIN; 1.
DR PANTHER; PTHR47761; C-TYPE LECTIN-RELATED; 1.
DR Pfam; PF00431; CUB; 4.
DR Pfam; PF07645; EGF_CA; 3.
DR Pfam; PF12661; hEGF; 3.
DR SMART; SM00042; CUB; 5.
DR SMART; SM00181; EGF; 9.
DR SMART; SM00179; EGF_CA; 6.
DR SUPFAM; SSF57196; EGF/Laminin; 5.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 5.
DR PROSITE; PS00010; ASX_HYDROXYL; 3.
DR PROSITE; PS01180; CUB; 6.
DR PROSITE; PS00022; EGF_1; 4.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 7.
DR PROSITE; PS01187; EGF_CA; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 67..103
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 160..196
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 198..239
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 292..331
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 377..422
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 427..462
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 463..503
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 612..740
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 750..890
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 891..1019
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1023..1141
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1147..1258
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1262..1385
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT REGION 1383..1453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1425..1445
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 186..195
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 229..238
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 431..441
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 452..461
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 493..502
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1468 AA; 163094 MW; 6AB19E0A9720D7D2 CRC64;
MKSRVSRLFE ASRIMLTEIR SLGTKHHNLS DLVHEINSTR KRDGLRRVRT VLLSLNRQIS
RLAHYLREDE CLKKPCRNGG TCFDQFDKYM CLCPPHFTVX XXXASRIMLT EIRSLGTKHH
NLSDLVHEIN STRKRDGLRR VRTVLLSLNR QISRLAHYLR EDECLKKPCR NGGTCFDQFD
KYMCLCPPHF TGPNCEFDVD ECAIHQGTSA GCQNNGTCEN HKGGFRCHCP HGFHGTLCQT
RSTACEFSMD LCGEHGHCLP TGMGPGGQPG YKCLCEWGFR PSNDTENPVC EDVDECLSKP
CYPGADCINL PGTFRCSGCP AGLRGNGLLC ADVDECEEDA LYDCSKEPKV ACLNTFGSYR
CGPCPAGYEG DGRTCLRHGA CADQPCHPEA RCVEMDPGSG SLFRCECPAG KTGSGVGGDG
CAPLQDEPSK CTRTCQNGGT CSEENGSEVC LCPMGRSGPS CEYIAVCGPE SACSGNGNCS
SYDATTGTLR CKCERGFYGE FCENELNGCS FYTTNATGVI TYPPAPDSFI SCIWMFDIPD
KMYIEFSLVN YTFSGGEGRG QIGFHSKDIV NVMNATHQFK QFTLSTRAFV ELLRPGQGLR
FALTWEAKNS GCGGLXXXXT WEAKNSACGG LFYPISEPYS TVVEAHAEDV FCIYDFEVLP
AYEMDVVIEE ISLQTRTVEN CTLNAIQVTA NPNYVVETTN ICGNRPPFRE TVTALRVRFT
NRYLGTRCGT PGCTSRFKIS VTPRVKEDAC GDVLTLSTEK ALEGTISSPG FDDPEEDGPP
KDDFCTWVIN ATSLSPAVYK KGMIESHYFG FRVAVDVLDV DMPSTKRGIC THSSLSFPLD
EYDFHSIPYD RSYCDTMKPR RQILSDGPTM KVAYRRKDSG RGFKLTYKPD CNHYYFEPNG
TIQSPHYPHA SPYAYKCTYT IFSQPTNAIR LKFNYIGVKT DIATCFYRFS EQEKLEDYIE
FSGGHKSNEQ INRRYVCPKY PFVMPMGEMV TSAQRPLTIT FSTSGSPQNT GFQFEYQAID
VGCGGVFSED AGVITSPNYP EKYLPHMYCV YQITVNPNKR VRLTFEVFDL EIVSNREECG
FDNVRVYNSF ETEEHHGKAH GKFCGSMTPP SILSDGNRMA VVFVSDRSVS GTGFSARWQS
VDDSIDCDRT FTASSGRIEF EAEKFRRVTQ CDYHIALPSA HRILLRVENI SAPCDQASLI
VKNGLSDLSP GFGGLYGNSE ICDDHPVKQL RSQGNRLFLR FRTSNARSTS FNVTYEQIDS
GCGGTMSGMS GAISAPQYPL KDSRSQNCEW HIAVAAGNRI RFQLSLIDDL NSADSSGFCS
VFAPNIIDIA DGPDANSNIL RRICKKETGA SSIDSETNEV TVRYRQHGGS HFPPLFGFLG
HFSTGRSHHE KKKLRSPSSS MHGHHSDGAP RRPSESGLPR QDSRRAFLPL EDRHACREPH
PADLPPLPRH RPTVLPLLAQ RRYHQVLQ
//
