ID A0A1I8AMK7_9BILA Unreviewed; 593 AA.
AC A0A1I8AMK7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=TWiK family of potassium channels protein 7 {ECO:0000313|WBParaSite:L893_g6984.t1};
OS Steinernema glaseri.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Steinernematidae;
OC Steinernema.
OX NCBI_TaxID=37863 {ECO:0000313|Proteomes:UP000095287, ECO:0000313|WBParaSite:L893_g6984.t1};
RN [1] {ECO:0000313|WBParaSite:L893_g6984.t1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
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DR AlphaFoldDB; A0A1I8AMK7; -.
DR WBParaSite; L893_g6984.t1; L893_g6984.t1; L893_g6984.
DR Proteomes; UP000095287; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR PANTHER; PTHR11003:SF240; TWIK FAMILY OF POTASSIUM CHANNELS; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 274..332
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 386..458
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
SQ SEQUENCE 593 AA; 67738 MW; A2BAA9DFCA4A5D87 CRC64;
MSLDVEDARR LRASIHVIGS LLDAEKPPQS SAATEHLWKN ALLEGARSAR ASVPLKKCLR
VLVCVTRFGA AKLLLRHLRM VKSNRFLKCL TPVVKLFDLG LAEISLYRVS TPPGEEDTSK
ECLRTPFFIS SKQRPKDLHL KSDLPRGPSF QLASASQRQV RHLQQEPPLC FRFVQRVYHE
YGLKHLILIF VLLFYTFFGA FLFLVIEGPT QKRMKDNISR NRSVFVTSLM SELFNNSDYL
VYIKGRTTNR IEEHLLQSFQ RYETQLDIRW SDQKMEWDYW NAILFAGTIC TTIGYGHIYP
ITTPGRLLTV VYALGGIPLV LLVLQDLGKL LTVGMKYPWY QFKRFIRRIL RIFTKQSLSD
MAAIEYRERT DLCVFDVPLP AAISLILVWI WLCSTVISYW GSNWTFVETC YFFFISLSTI
GLGDLVPHNP HLLLMMFGFI LVGLSLVSMV LNLLQNKMRS TYEGRHSDGA RRSSILDATT
LGILQCFEER TKMEEKLRRC ATRSAQTTLC LPVARQLILT EDGVQWIPHG SYSAYTLKSP
DEVTALVEMR ADVTVLSALG ENEDEHDDSS ASLLSEEFSA ETPTILPPFL FQC
//
