ID A0A1I8AYG2_MELHA Unreviewed; 129 AA.
AC A0A1I8AYG2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 9 {ECO:0000256|ARBA:ARBA00020636, ECO:0000256|RuleBase:RU364145};
DE AltName: Full=Mediator complex subunit 9 {ECO:0000256|ARBA:ARBA00031260, ECO:0000256|RuleBase:RU364145};
GN Name=MED9 {ECO:0000256|RuleBase:RU364145};
OS Meloidogyne hapla (Root-knot nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC Meloidogyne.
OX NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig108.frz3.gene34};
RN [1] {ECO:0000313|WBParaSite:MhA1_Contig108.frz3.gene34}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC the regulated transcription of nearly all RNA polymerase II-dependent
CC genes. Mediator functions as a bridge to convey information from gene-
CC specific regulatory proteins to the basal RNA polymerase II
CC transcription machinery. Mediator is recruited to promoters by direct
CC interactions with regulatory proteins and serves as a scaffold for the
CC assembly of a functional preinitiation complex with RNA polymerase II
CC and the general transcription factors. {ECO:0000256|RuleBase:RU364145}.
CC -!- SUBUNIT: Component of the Mediator complex.
CC {ECO:0000256|RuleBase:RU364145}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364145}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 9 family.
CC {ECO:0000256|ARBA:ARBA00008089, ECO:0000256|RuleBase:RU364145}.
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DR AlphaFoldDB; A0A1I8AYG2; -.
DR WBParaSite; MhA1_Contig108.frz3.gene34; MhA1_Contig108.frz3.gene34; MhA1_Contig108.frz3.gene34.
DR Proteomes; UP000095281; Unplaced.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR InterPro; IPR011425; Med9.
DR Pfam; PF07544; Med9; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|RuleBase:RU364145};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364145};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU364145};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU364145}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 129 AA; 14619 MW; 657331409CBB7C2C CRC64;
MGEGDQQQQT TEDSSTTSLK SLNQLSQTLQ NLLNRFGLGP QVTCARSQNF YFSSDKTGPE
LHNRISQLRT SIERLRTCTN SIENINRSAE DQWAKIEDLR RQLIKKNEFF KRFGEEKVGE
GGSSATTSQ
//
