ID   A0A1I8AYG7_MELHA        Unreviewed;       629 AA.
AC   A0A1I8AYG7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=RNB domain-containing protein {ECO:0000313|WBParaSite:MhA1_Contig108.frz3.gene39};
OS   Meloidogyne hapla (Root-knot nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC   Meloidogyne.
OX   NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig108.frz3.gene39};
RN   [1] {ECO:0000313|WBParaSite:MhA1_Contig108.frz3.gene39}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the RNR ribonuclease family.
CC       {ECO:0000256|ARBA:ARBA00005785}.
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DR   AlphaFoldDB; A0A1I8AYG7; -.
DR   WBParaSite; MhA1_Contig108.frz3.gene39; MhA1_Contig108.frz3.gene39; MhA1_Contig108.frz3.gene39.
DR   OMA; WELNEEA; -.
DR   Proteomes; UP000095281; Unplaced.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR   Gene3D; 2.40.50.690; -; 1.
DR   Gene3D; 2.40.50.700; -; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR041505; Dis3_CSD2.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR001900; RNase_II/R.
DR   InterPro; IPR033771; Rrp44_CSD1.
DR   PANTHER; PTHR23355:SF35; EXOSOME COMPLEX EXONUCLEASE RRP44; 1.
DR   PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR   Pfam; PF17849; OB_Dis3; 1.
DR   Pfam; PF00773; RNB; 1.
DR   Pfam; PF17216; Rrp44_CSD1; 1.
DR   SMART; SM00955; RNB; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022722};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          426..629
FT                   /note="Ribonuclease II/R"
FT                   /evidence="ECO:0000259|SMART:SM00955"
FT   REGION          255..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..285
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   629 AA;  72122 MW;  D5D5D3F5884B387C CRC64;
     MELNVKQSGI EKRTISTAYY KTRSGKINKR VHELYLRNDI PCGFSRCLKC RYNSEALKPL
     QFFENGALSK SVQYPHFLLL DGPSIMKFID VLDDTRVFRQ EHCLISGSKF LFDHWQEFTV
     RPLVVCSSEE AVARVSKDYP HAITMIDYVK GIQGCEPLIQ RLNDLSKKER RGRALFPEYW
     TQDKLLDGLS KGNLKKGKFQ ISPENYLEAF VEFDMEDQWF VQGSLNMNRA VHGDVVVAQL
     LPENEWTAPE KTIRLRDAEE SQNGGNNLTV DDDEGGEEEA QEDLEESEAP AKKSRKEVLP
     SARIVGILRR NWRHYCGIIL PPNMPGTRQF LFAPSERLIP RIRIETSYYE QLIGKKVLVQ
     IDSWPQDSHY PRGHYIRVIG NEGERKTEDE VILLEHEVPY DEFSPAVLAC LPEMPWSPHP
     LDPPEREDLT SLDICSVDPE GCTDIDDAVH CRELGPNRYE VGVHIADVTH FVRPGTAIDQ
     TAAERSTSVY LCGRRIDMLP SLLSTNLCSL RGNELRYAFS VIWELNEEAQ IQNVRFCKSL
     IHSRAALTYQ RAQELIDDEQ YNSRRRTVGA LELASSEIRF DIDPETGAPI KVLEKQHLDT
     MSMIEEFMLL ANISVAEKIL HEYPVNTLF
//