ID   A0A1I8AZK8_MELHA        Unreviewed;       438 AA.
AC   A0A1I8AZK8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Pept_C1 domain-containing protein {ECO:0000313|WBParaSite:MhA1_Contig1089.frz3.gene15};
OS   Meloidogyne hapla (Root-knot nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC   Meloidogyne.
OX   NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig1089.frz3.gene15};
RN   [1] {ECO:0000313|WBParaSite:MhA1_Contig1089.frz3.gene15}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase C1 family.
CC       {ECO:0000256|ARBA:ARBA00008455}.
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DR   AlphaFoldDB; A0A1I8AZK8; -.
DR   WBParaSite; MhA1_Contig1089.frz3.gene15; MhA1_Contig1089.frz3.gene15; MhA1_Contig1089.frz3.gene15.
DR   OMA; NAHEFQA; -.
DR   Proteomes; UP000095281; Unplaced.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR000169; Pept_cys_AS.
DR   InterPro; IPR013128; Peptidase_C1A.
DR   InterPro; IPR000668; Peptidase_C1A_C.
DR   PANTHER; PTHR12411:SF895; CATHEPSIN B; 1.
DR   PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR   Pfam; PF00112; Peptidase_C1; 1.
DR   PRINTS; PR00705; PAPAIN.
DR   SMART; SM00645; Pept_C1; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670}; Signal {ECO:0000256|SAM:SignalP};
KW   Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..438
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018547750"
FT   DOMAIN          182..435
FT                   /note="Peptidase C1A papain C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00645"
FT   REGION          129..173
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   438 AA;  49849 MW;  AD8054D6AFF4B4C8 CRC64;
     MKITKIFTIL LLLYFASFTH QQIIDILLGP ILNLLNSILG GLLNIDDKRK LAEILLKIER
     EYSVKLSPEE IKEKVDHFLQ LKTEIDGKWG FEMTVYFFLP KELQIKLGGG NGWLSPGEDP
     NGEFHIGEVT GTPKIGPPLE GGPINGEQEE PDEESPLEEE PVETNKTYNE EHPRDKRASC
     TYKNVFSSRV KWSECAPIIN RITDQGQCGS CWAVSTSGAF TDRLCIERAK KGWKTPNDAS
     YIYSALDALS CSGGGNCVSG RPATVWDWMY RWGICTGTSY NTYEGCKPYP FSSGGRTYTP
     DCYESCDSNW NTRYFDDKRK VKSWRYVSGN SININDIMRE LETNGPVIGI FRIYTDLFGF
     IGDGVYIKSR SAQERENHVV EIIGYGTQVC NGYETDYWLI KNSWNPSRFG DNGFFKMRRG
     WNECYIESNQ FSYGIPYV
//