ID   A0A1I8B4U1_MELHA        Unreviewed;       820 AA.
AC   A0A1I8B4U1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Aromatic-L-amino-acid decarboxylase {ECO:0000313|WBParaSite:MhA1_Contig134.frz3.gene32};
OS   Meloidogyne hapla (Root-knot nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC   Meloidogyne.
OX   NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig134.frz3.gene32};
RN   [1] {ECO:0000313|WBParaSite:MhA1_Contig134.frz3.gene32}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|ARBA:ARBA00009533}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A1I8B4U1; -.
DR   WBParaSite; MhA1_Contig134.frz3.gene32; MhA1_Contig134.frz3.gene32; MhA1_Contig134.frz3.gene32.
DR   Proteomes; UP000095281; Unplaced.
DR   GO; GO:0016831; F:carboxy-lyase activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   CDD; cd06450; DOPA_deC_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 1.20.1340.10; dopa decarboxylase, N-terminal domain; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR010977; Aromatic_deC.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR11999; GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE; 1.
DR   PANTHER; PTHR11999:SF177; MIP05841P; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 2.
DR   PRINTS; PR00800; YHDCRBOXLASE.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239}.
FT   REGION          46..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          121..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          623..669
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          685..709
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..144
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        631..669
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   820 AA;  92213 MW;  FA632F0A6D186D0E CRC64;
     MIREILVKVI EKPSPIVDPY FITSLEFLWV MECFEDDKLT QKLSFSSSTS TATPLPSSTS
     GVPTSNFVPS PHGSITQMNK IEQLRDKINE ALIEGQNNRK RTAADQLLQQ IAEHFSKVNL
     NDSRKGSSNV DDSCGSSRQR LGAAKSTAGM NAVEFRRRGR QMVDYITDYM ENIENRRVVP
     SIEPGYLKEL LPLHAPQTAE PFERLLQDFE SYIMPGVTHW THPRFHAYFP AGNSFPSILA
     DMLSDALGAI GFSWAACPAM TELEIHMLQW LGEMIGLPVA FLPFTENGTG GGVIQVITVN
     ALIEAQSSAS ECNFVALLAA RFEIMKELRQ RFPFVEEGLL MSKLIAYCSK EAHSSVEKAA
     MIAMIKLRIL ETDSSFRLRG ETLQTAVSED RNLGLIPFFV STTLGTTSCC SFDVLSEVGP
     VCTHNGLWLH VDAAYAGSAM ICPEFRYLMA GIEHAMSFNT NPNKWMLVNR TSDYRHWGIP
     LSRRFRSLKL WFVIRSYGIE GLQRYIREHV RLAKLFECLL LADDQLFEVV AEVLMGLVCF
     RMKASDELNQ LLLTKLNSSG RIHMVPASLN DRFVIRFCVC YENATERDIQ IAYEIIKQTA
     MSLREPIPEP IAENYELEME EAEQYDQMMQ DKQKNRNSPN IELNRNSSLR RQSIGSSSIN
     TPSYPQQQQN LQQNIQQMGN SPLAIGIGSE QTIGGHSPSS LTSSTGADRR RLHTLAEKRS
     FLVRMVSDPK CYNPKIVRHL NMRAHNQTSA ELFRDRTLRQ AIQQGSFQQR SSLGAGTSHG
     RIGANAPFSS GKYACMSIDQ GSDEDDYQSL YFQNDQNLGI
//