ID   A0A1I8B5B4_MELHA        Unreviewed;       189 AA.
AC   A0A1I8B5B4;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Clat_adaptor_s domain-containing protein {ECO:0000313|WBParaSite:MhA1_Contig1418.frz3.gene3};
OS   Meloidogyne hapla (Root-knot nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC   Meloidogyne.
OX   NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig1418.frz3.gene3};
RN   [1] {ECO:0000313|WBParaSite:MhA1_Contig1418.frz3.gene3}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- FUNCTION: Part of the AP-3 complex, an adaptor-related complex which is
CC       not clathrin-associated. The complex is associated with the Golgi
CC       region as well as more peripheral structures. It facilitates the
CC       budding of vesicles from the Golgi membrane and may be directly
CC       involved in trafficking to lysosomes. In concert with the BLOC-1
CC       complex, AP-3 is required to target cargos into vesicles assembled at
CC       cell bodies for delivery into neurites and nerve terminals.
CC       {ECO:0000256|ARBA:ARBA00025605}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC       {ECO:0000256|ARBA:ARBA00004180}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004180}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004180}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004287}.
CC   -!- SIMILARITY: Belongs to the adaptor complexes small subunit family.
CC       {ECO:0000256|ARBA:ARBA00006972}.
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DR   AlphaFoldDB; A0A1I8B5B4; -.
DR   WBParaSite; MhA1_Contig1418.frz3.gene3; MhA1_Contig1418.frz3.gene3; MhA1_Contig1418.frz3.gene3.
DR   OMA; VYKTFAT; -.
DR   Proteomes; UP000095281; Unplaced.
DR   GO; GO:0030123; C:AP-3 adaptor complex; IEA:InterPro.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006896; P:Golgi to vacuole transport; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   CDD; cd14834; AP3_sigma; 1.
DR   Gene3D; 3.30.450.60; -; 1.
DR   InterPro; IPR016635; AP_complex_ssu.
DR   InterPro; IPR022775; AP_mu_sigma_su.
DR   InterPro; IPR027155; APS3.
DR   InterPro; IPR000804; Clathrin_sm-chain_CS.
DR   InterPro; IPR011012; Longin-like_dom_sf.
DR   PANTHER; PTHR11753; ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY; 1.
DR   PANTHER; PTHR11753:SF2; ADAPTOR PROTEIN COMPLEX AP-3 SMALL CHAIN SIGMA3; 1.
DR   Pfam; PF01217; Clat_adaptor_s; 1.
DR   SUPFAM; SSF64356; SNARE-like; 1.
DR   PROSITE; PS00989; CLAT_ADAPTOR_S; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Transport {ECO:0000256|ARBA:ARBA00022927}.
FT   DOMAIN          1..147
FT                   /note="AP complex mu/sigma subunit"
FT                   /evidence="ECO:0000259|Pfam:PF01217"
SQ   SEQUENCE   189 AA;  21855 MW;  398B00533FF0F448 CRC64;
     MIKAILIFNN HGKPRLLKFY IRYTEDEQQQ IVRETFQQVS KRDDNVCNFL EGGTLIGGSD
     FKLIYRHYAT LYFVFCVDSS ESELGILDLI QVFVETLDRC FENVCELDMI FHVNKVHNIL
     NEIVMGGMVL ETNMNEILLR VQEQDKIEKQ EAGITAAPAR AVSAVKNMNI PQQIKRFKIT
     GFTFKNCCF
//