ID   A0A1I8B6N5_MELHA        Unreviewed;       418 AA.
AC   A0A1I8B6N5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=PDZ domain-containing protein {ECO:0000313|WBParaSite:MhA1_Contig1477.frz3.gene10};
OS   Meloidogyne hapla (Root-knot nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC   Meloidogyne.
OX   NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig1477.frz3.gene10};
RN   [1] {ECO:0000313|WBParaSite:MhA1_Contig1477.frz3.gene10}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the DSH family. {ECO:0000256|ARBA:ARBA00008735}.
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DR   AlphaFoldDB; A0A1I8B6N5; -.
DR   WBParaSite; MhA1_Contig1477.frz3.gene10; MhA1_Contig1477.frz3.gene10; MhA1_Contig1477.frz3.gene10.
DR   Proteomes; UP000095281; Unplaced.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:InterPro.
DR   CDD; cd04438; DEP_dishevelled; 1.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 2.40.240.130; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000591; DEP_dom.
DR   InterPro; IPR001158; DIX.
DR   InterPro; IPR038207; DIX_dom_sf.
DR   InterPro; IPR015506; Dsh/Dvl-rel.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10878; SEGMENT POLARITY PROTEIN DISHEVELLED; 1.
DR   PANTHER; PTHR10878:SF24; SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG MIG-5; 1.
DR   Pfam; PF00610; DEP; 1.
DR   Pfam; PF00778; DIX; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   SMART; SM00049; DEP; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50186; DEP; 1.
DR   PROSITE; PS50106; PDZ; 1.
PE   3: Inferred from homology;
FT   DOMAIN          106..172
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          314..392
FT                   /note="DEP"
FT                   /evidence="ECO:0000259|PROSITE:PS50186"
SQ   SEQUENCE   418 AA;  47493 MW;  ED4AC6AD62661EBB CRC64;
     MSEVQIPLDR LTLGDFKRVF NRKGYSYFCK EWDPNLKRSS SSIFRRGPLP GAPMPSAESM
     TESAAERTLL VNTSTARQKR LRKQRYVPST ISSESESTYS LPRIEEVKLR LQDAPLGISV
     ASQCGSIFIY HIQNGSAAER CCRLEVGDQI VQIDETRFED LNEKQALEVL KKLSYVKNKN
     CVEPFAEIPP VESRIGINQI TGALPIDEFK VKNQTIDETS DEEKAAYLDR RNGVGARLVP
     IIHQVRFHQQ QKADVKQRIK MVDLENNPTT SSFPITLGIV EECSPHPDCH PPLIQLPLHA
     AMDPIVILRR MVELDSGLEI RNRKWLKIPV PMSFIGDEMI DWLIANVQGF RDRRHARSFA
     SNLLAQGLIK HDEIIASRLH FEEEQKQLLL KHQQNIDCQN TSIKKAPAPP PESNTEIT
//