ID   A0A1I8BBZ7_MELHA        Unreviewed;       367 AA.
AC   A0A1I8BBZ7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=FAD synthase {ECO:0000256|ARBA:ARBA00012393};
DE            EC=2.7.7.2 {ECO:0000256|ARBA:ARBA00012393};
DE   AltName: Full=FAD pyrophosphorylase {ECO:0000256|ARBA:ARBA00031145};
DE   AltName: Full=FMN adenylyltransferase {ECO:0000256|ARBA:ARBA00031871};
OS   Meloidogyne hapla (Root-knot nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC   Meloidogyne.
OX   NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig1878.frz3.fgene1};
RN   [1] {ECO:0000313|WBParaSite:MhA1_Contig1878.frz3.fgene1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + FMN + H(+) = diphosphate + FAD; Xref=Rhea:RHEA:17237,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:57692, ChEBI:CHEBI:58210; EC=2.7.7.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00001332};
CC   -!- PATHWAY: Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step
CC       1/1. {ECO:0000256|ARBA:ARBA00004726}.
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DR   AlphaFoldDB; A0A1I8BBZ7; -.
DR   WBParaSite; MhA1_Contig1878.frz3.fgene1; MhA1_Contig1878.frz3.fgene1; MhA1_Contig1878.frz3.fgene1.
DR   OMA; DEESAEC; -.
DR   Proteomes; UP000095281; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   CDD; cd01713; PAPS_reductase; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR002500; PAPS_reduct.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR23293:SF9; FAD SYNTHASE; 1.
DR   PANTHER; PTHR23293; FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE; 1.
DR   Pfam; PF01507; PAPS_reduct; 1.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          244..318
FT                   /note="Phosphoadenosine phosphosulphate reductase"
FT                   /evidence="ECO:0000259|Pfam:PF01507"
SQ   SEQUENCE   367 AA;  43094 MW;  8205033513997B15 CRC64;
     MKGIIHTNSY KSLFLSFYSR IIQLSKNWVN NKPKNIFKEI ELIKNILMSE IHPIWNLERI
     NGEKLFNRLK DDEESAECSD CKIKLKILDF GFTTLIQHIS SSAHSESNYK EKFQLLIKEN
     GKNNYLNISF DPRPWENAYE KLEAFQINFQ SQEISNKLKG ALQTIEEILN KYSMEQISLS
     FNGGKDCTLL LHLFRACVNK KYNNQKQINS FFIKSDDEFT EVVNFVHSIS EKCGLIYLKN
     EKPEIVATLM GSRYSDPKAA KMKSKCEWTE TGWPSFLRVC PLLDFSYSDI WILLRYLCIP
     YCCLYDQGYS SLGEKKRTAK NPHLKIIVKE NGEEGNERYL PAYMLKDEKF ERVFREDRVS
     EDECLRK
//