ID   A0A1I8BC19_MELHA        Unreviewed;       266 AA.
AC   A0A1I8BC19;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=ceramide glucosyltransferase {ECO:0000256|ARBA:ARBA00012699};
DE            EC=2.4.1.80 {ECO:0000256|ARBA:ARBA00012699};
OS   Meloidogyne hapla (Root-knot nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC   Meloidogyne.
OX   NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig1792.frz3.gene3};
RN   [1] {ECO:0000313|WBParaSite:MhA1_Contig1792.frz3.gene3}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- PATHWAY: Lipid metabolism; sphingolipid metabolism.
CC       {ECO:0000256|ARBA:ARBA00004760}.
CC   -!- PATHWAY: Sphingolipid metabolism. {ECO:0000256|ARBA:ARBA00004991}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC       {ECO:0000256|ARBA:ARBA00006739}.
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DR   AlphaFoldDB; A0A1I8BC19; -.
DR   WBParaSite; MhA1_Contig1792.frz3.gene3; MhA1_Contig1792.frz3.gene3; MhA1_Contig1792.frz3.gene3.
DR   OMA; VIHITAI; -.
DR   UniPathway; UPA00222; -.
DR   Proteomes; UP000095281; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008120; F:ceramide glucosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102769; F:dihydroceramide glucosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR025993; Ceramide_glucosylTrfase.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR12726; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR12726:SF0; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR   Pfam; PF13506; Glyco_transf_21; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        52..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   266 AA;  30203 MW;  031146C64734D939 CRC64;
     MSIEYYQSSS SQPGPSEEAL PSELDTSLID TDIPSNQLSF GIGTEQLALQ RIFASAGILF
     IMGIYLLHIV SIIYGRSRLH KTFLSINRED EEHEDGNHEP KQQQNKLNKI NLSSQLPGVS
     ILKPLVGIDD NLEENLESFF LLDYPQFELL FCLYSRQDPA YEVAQRLCSK YPKVDARIFI
     GGQRVGLNPK INNMFPGYVA SKYSHLLISD QGIYMRQNAL TDMVLCMLER TDIALVTQTP
     FCKDRVGIWA TLEQVEFFVI INIKLN
//