ID   A0A1I8BDB2_MELHA        Unreviewed;       598 AA.
AC   A0A1I8BDB2;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Aa_trans domain-containing protein {ECO:0000313|WBParaSite:MhA1_Contig1991.frz3.gene6};
OS   Meloidogyne hapla (Root-knot nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC   Meloidogyne.
OX   NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig1991.frz3.gene6};
RN   [1] {ECO:0000313|WBParaSite:MhA1_Contig1991.frz3.gene6}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane
CC       {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004155}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC       SLC38A9 subfamily. {ECO:0000256|ARBA:ARBA00038442}.
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DR   AlphaFoldDB; A0A1I8BDB2; -.
DR   WBParaSite; MhA1_Contig1991.frz3.gene6; MhA1_Contig1991.frz3.gene6; MhA1_Contig1991.frz3.gene6.
DR   OMA; EYCAVVF; -.
DR   Proteomes; UP000095281; Unplaced.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   PANTHER; PTHR22950; AMINO ACID TRANSPORTER; 1.
DR   PANTHER; PTHR22950:SF244; SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 9; 1.
DR   Pfam; PF01490; Aa_trans; 2.
PE   3: Inferred from homology;
KW   Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        151..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        325..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        351..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        392..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        433..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        478..499
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        511..536
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        542..564
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        576..597
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          150..257
FT                   /note="Amino acid transporter transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF01490"
FT   DOMAIN          334..590
FT                   /note="Amino acid transporter transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF01490"
SQ   SEQUENCE   598 AA;  67326 MW;  E629D1302350E1F5 CRC64;
     MASYSGEFTT LNQNAPQFRL EGFPENEQEG VPFARSVDNV LLTRNEARQV MQKPVNTTSE
     NAASVNLPRR PYLFVPPQSD SNASLLSSTI PVENRRDVIN RDHNMAIRYR FFNRLDPGGL
     HLLMPIHVIP TSIFSVLPFN EFKDSNGKQS SIVTIFSIWN TMVGTSLLAV PWALQQAGLV
     LGIVLMLIMA GIAFYTAYRI IESPNSLALE TSTPDFSDVC RFLWGKWLEY FAVFFSVCVL
     VGGVILYFVL MSNFLYFTGN VIYESLQQNS TILPIGFNQT CDVYCPKQIE NAFPNDFLSL
     IYRFSPNGLL SKISLGDSDS SFQKIWRLQG GVPLILAFCI FPLLNFRSPG FFMRFNGLGT
     ISVVYLICFT LVKSAECGLN LDFTNPLSKN YVQLFNWKFP ALTGTLALAY FIHNAILTIL
     RNQKHPENNA RDLLIGYFLS AGCYIIISLF FFTTFPTYRN CISDNFLNNF ASGDMLSAIA
     RVFLLFQMLT VLPLLMYLIR VQFSYVFAGT VYPGLFYVLL INGGILTIAL FFAVVYPHVG
     PIIRYVGSIC GLVYMFILPC AVHLKRLQIQ GRLNNVQIAI HIAIMLCGVL NLLAQFFV
//