ID A0A1I8BM82_MELHA Unreviewed; 278 AA.
AC A0A1I8BM82;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Neur_chan_LBD domain-containing protein {ECO:0000313|WBParaSite:MhA1_Contig338.frz3.gene17};
OS Meloidogyne hapla (Root-knot nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC Meloidogyne.
OX NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig338.frz3.gene17};
RN [1] {ECO:0000313|WBParaSite:MhA1_Contig338.frz3.gene17}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
CC {ECO:0000256|RuleBase:RU000687}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU000687}.
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DR AlphaFoldDB; A0A1I8BM82; -.
DR WBParaSite; MhA1_Contig338.frz3.gene17; MhA1_Contig338.frz3.gene17; MhA1_Contig338.frz3.gene17.
DR OMA; WIHERIC; -.
DR Proteomes; UP000095281; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR CDD; cd18993; LGIC_ECD_GluCl; 1.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR006201; Neur_channel.
DR InterPro; IPR018000; Neurotransmitter_ion_chnl_CS.
DR PANTHER; PTHR18945:SF504; GLUTAMATE-GATED CHLORIDE CHANNEL SUBUNIT BETA; 1.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR Pfam; PF02931; Neur_chan_LBD; 1.
DR PRINTS; PR00252; NRIONCHANNEL.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1.
DR PROSITE; PS00236; NEUROTR_ION_CHANNEL; 1.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU000687};
KW Ion transport {ECO:0000256|RuleBase:RU000687};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU000687};
KW Transmembrane {ECO:0000256|RuleBase:RU000687};
KW Transmembrane helix {ECO:0000256|RuleBase:RU000687};
KW Transport {ECO:0000256|RuleBase:RU000687}.
FT TRANSMEM 255..276
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU000687"
FT DOMAIN 33..254
FT /note="Neurotransmitter-gated ion-channel ligand-binding"
FT /evidence="ECO:0000259|Pfam:PF02931"
SQ SEQUENCE 278 AA; 32308 MW; 027810D76FB34341 CRC64;
MLNSTNSTNF TINQQNFNLT TNIWSLSGRE DHHEILDDLL KNYDQSRIRP PIDLDSNETA
VRVRVNILVR MLSKIDVVNM EYTIQITFRE QWIDKRLNYQ NHVFTPPRPL PPFLVVPHVK
ARIWFPDTFF PTEKSAHRHM IDSENMLVRI YPNGSVLYSS RLSLVCSCPM YLQLYPLDVQ
FCDFDLISYA HTTRDIIYEW AGNGSLHDSV QIKQGVGQDL PDFRLDYIDT GVECTSHTTT
GSYACLRMRI RLSRLFTYFV LQLYIPTSMV VCVSLVGV
//
