ID A0A1I8BUA1_MELHA Unreviewed; 550 AA.
AC A0A1I8BUA1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Moesin/ezrin/radixin homolog 1 {ECO:0000256|ARBA:ARBA00022025};
OS Meloidogyne hapla (Root-knot nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC Meloidogyne.
OX NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig546.frz3.gene2};
RN [1] {ECO:0000313|WBParaSite:MhA1_Contig546.frz3.gene2}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, adherens junction
CC {ECO:0000256|ARBA:ARBA00004536}. Cell projection, microvillus
CC {ECO:0000256|ARBA:ARBA00004105}. Cell projection, rhabdomere
CC {ECO:0000256|ARBA:ARBA00043944}. Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A1I8BUA1; -.
DR WBParaSite; MhA1_Contig546.frz3.gene2; MhA1_Contig546.frz3.gene2; MhA1_Contig546.frz3.gene2.
DR OMA; WADHKNT; -.
DR Proteomes; UP000095281; Unplaced.
DR GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13194; FERM_C_ERM; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 6.10.360.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR011174; ERM.
DR InterPro; IPR011259; ERM_C_dom.
DR InterPro; IPR041789; ERM_FERM_C.
DR InterPro; IPR046810; ERM_helical.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR008954; Moesin_tail_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23281; MERLIN/MOESIN/EZRIN/RADIXIN; 1.
DR PANTHER; PTHR23281:SF18; MOESIN_EZRIN_RADIXIN HOMOLOG 1; 1.
DR Pfam; PF00769; ERM_C; 1.
DR Pfam; PF20492; ERM_helical; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PIRSF; PIRSF002305; ERM; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF48678; Moesin tail domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136}.
FT DOMAIN 1..301
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT COILED 275..421
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 481..508
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 550 AA; 65335 MW; 3BF771E58D6BEBAF CRC64;
MDAELEFSIQ SSTSGKQLFD QVVKTINLRE IWYFGLQYTD NKGFSTWLKL NKKVLKQDVK
KEPILQFKFR AKFYPEDVAE EIIQDVTLRL FYLQVKDLIL SDEVYCPPDQ AVLLASYAMQ
AKYGDYIKDK HLPGTLANDR LLPQRVLNQF KMNINEWEVR VMNWWADHRG MNRETAMIEY
LKIAQDLDMY GVNYFEIRNK KDTELYLGVD SLGLNIYDKS DKLSPKVGFP WSEIRNISFN
DKKFVIKPVD KKSQALCMGN HELYMRRRKP DSIEVQQMKQ QAKEERIQRQ MEQERLQKEM
KARELAEQKQ LEYKARMLSM QDEMEQTHKE LEAAQDRIRR LEDELYELNQ AKRLLEQKEE
ELHELNRQMQ SERAMSSEER NRLLREIAAQ ETQVTAMRSE VQIKTDKMNK LKEEVEKGQH
KKVVPNTAVT HVHTGIYDNN ANGGNGHLPR EFNDPGDLTN AHVELTYEAE ENNYPQRELD
RQNVTDQNQS LKKKLEMLTK ELDNARNQQA ITDFDILHME NRRQGRDRYK TLRQIRCGNT
KRRIDQYENM
//
