ID   A0A1I8BZU6_MELHA        Unreviewed;       558 AA.
AC   A0A1I8BZU6;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Degenerin del-1 {ECO:0000313|WBParaSite:MhA1_Contig841.frz3.gene17};
OS   Meloidogyne hapla (Root-knot nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Tylenchomorpha; Tylenchoidea; Meloidogynidae; Meloidogyninae;
OC   Meloidogyne.
OX   NCBI_TaxID=6305 {ECO:0000313|Proteomes:UP000095281, ECO:0000313|WBParaSite:MhA1_Contig841.frz3.gene17};
RN   [1] {ECO:0000313|WBParaSite:MhA1_Contig841.frz3.gene17}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
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DR   AlphaFoldDB; A0A1I8BZU6; -.
DR   WBParaSite; MhA1_Contig841.frz3.gene17; MhA1_Contig841.frz3.gene17; MhA1_Contig841.frz3.gene17.
DR   OMA; FQYRTII; -.
DR   Proteomes; UP000095281; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690:SF242; DEGENERIN UNC-8; 1.
DR   Pfam; PF00858; ASC; 2.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|RuleBase:RU000679}.
SQ   SEQUENCE   558 AA;  64133 MW;  E6BA0ABFD85C8EB8 CRC64;
     MEHGPREYLS CKDIGVDFCA RTSSHGIPFV GCNLNAFKLS EVRKYEEIEQ GHCSFCSHSN
     TCDDPDLPNN KTNNIKLIPP SIPCLCQPIS HYCIKDNRKL GQDFEWWNPH NYTIYPSTTR
     SPPSQMEEAF GLEDLKDRGA ITTRTKENLI FLVAGMSRQI RQSLSYTLHE FVLRCSFNSK
     DCDLNSWTFN FNDSVELKNS RAGPMYGLRL LLNVNQSDYM PTTEAAGVRI VVHEQDQEPF
     PDTFGFQHII LERCGCGDPR KPFYFYFSNE IYLKFSCFPL PNESEDRPCD ARNPKERACL
     SNQTAVLGGF HHLTHDCHCV QPCTENTFET AYSAASWPAQ NFNIGQDDCA LVLGNNFTMA
     SCTEYYRKNT AYIEIYYEQL NYEKLKETPG YTAINLFSDL GGNIGLWIGF SLITVLEIVE
     LVFECFAYGC KQCIYRPLQR KAQIRRNRRL SSNEVNLNGE IEQKEGFRHA GAKISRHISL
     LEPGYRQEGP AHGGHSRQYQ RRWAGTARSW KRPLTQHPTN IPPFFEQKFV EVEKEKTKEN
     GSGIHDSYNY TVKFIYFP
//