ID A0A1I8C2R8_9BILA Unreviewed; 507 AA.
AC A0A1I8C2R8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=cytochrome-b5 reductase {ECO:0000256|ARBA:ARBA00012011};
DE EC=1.6.2.2 {ECO:0000256|ARBA:ARBA00012011};
OS Rhabditophanes sp. KR3021.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Alloionematidae;
OC Rhabditophanes.
OX NCBI_TaxID=114890 {ECO:0000313|Proteomes:UP000095286, ECO:0000313|WBParaSite:RSKR_0000000400.1};
RN [1] {ECO:0000313|WBParaSite:RSKR_0000000400.1}
RP IDENTIFICATION.
RC STRAIN=KR3021 {ECO:0000313|WBParaSite:RSKR_0000000400.1};
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR AlphaFoldDB; A0A1I8C2R8; -.
DR WBParaSite; RSKR_0000000400.1; RSKR_0000000400.1; RSKR_0000000400.
DR Proteomes; UP000095286; Unplaced.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd06183; cyt_b5_reduct_like; 1.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR001834; CBR-like.
DR InterPro; IPR008333; Cbr1-like_FAD-bd_dom.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR018506; Cyt_B5_heme-BS.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR19370; NADH-CYTOCHROME B5 REDUCTASE; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR Pfam; PF00970; FAD_binding_6; 1.
DR PRINTS; PR00406; CYTB5RDTASE.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS00191; CYTOCHROME_B5_1; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 71..147
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
FT DOMAIN 275..375
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 507 AA; 57636 MW; 4BC71D760F4C93C9 CRC64;
MLAAPVPFLY EDDIIDEQMY SDDTYIEEID TSTGGDRITK TGRNKVNLGP GKSLSDWIVK
AGERNGCGKE KDLISEVELA KHDKINDCWI AIHGKVYDVT DYLAYHPGGV PEIVAHAGKD
ATLAFEEIHG WINYQGFLRN YCMGVYRGAR VQSRKLECQD SLDTTNAELS MKILRDKEIR
IKKMCDSSVA IISNKWKNLG LNNFTFSVTD GILSVRIKHF HDIPYQFEFP ADDTMEFGNF
SVICSRNKFT IESKKPLNAQ IFDERKWSVS EAVGTRYHRS QIVEKTKVTH DTFKFRLSFP
LNSCIRIPVG HHVVLRHLVR NNRVSRAYTP ISVTDKEIEF LIKVYDDGLL TPTLGSLEVD
NFIEMSDSIG KIDFTEGFEN ERKVLCLGAG TGLTPMLRLI NDRIDKGIDT ALLLFNKKFE
DIVPDIFLPT TNKHFYFKNI LSQETNESVN SKHEYALGKI SCSVLEQLAD IHSRQIFICG
PYNFTSLAQS LLKELNVFPE NVHVFDG
//
