ID   A0A1I8CJZ9_9BILA        Unreviewed;       773 AA.
AC   A0A1I8CJZ9;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=PDZ domain-containing protein {ECO:0000313|WBParaSite:RSKR_0000506300.1};
OS   Rhabditophanes sp. KR3021.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Alloionematidae;
OC   Rhabditophanes.
OX   NCBI_TaxID=114890 {ECO:0000313|Proteomes:UP000095286, ECO:0000313|WBParaSite:RSKR_0000506300.1};
RN   [1] {ECO:0000313|WBParaSite:RSKR_0000506300.1}
RP   IDENTIFICATION.
RC   STRAIN=KR3021 {ECO:0000313|WBParaSite:RSKR_0000506300.1};
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A1I8CJZ9; -.
DR   WBParaSite; RSKR_0000506300.1; RSKR_0000506300.1; RSKR_0000506300.
DR   Proteomes; UP000095286; Unplaced.
DR   CDD; cd00071; GMPK; 1.
DR   CDD; cd00992; PDZ_signaling; 3.
DR   Gene3D; 2.30.42.10; -; 3.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR008145; GK/Ca_channel_bsu.
DR   InterPro; IPR008144; Guanylate_kin-like_dom.
DR   InterPro; IPR020590; Guanylate_kinase_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR23119; DISCS LARGE; 1.
DR   PANTHER; PTHR23119:SF51; DISKS LARGE 1 TUMOR SUPPRESSOR PROTEIN; 1.
DR   Pfam; PF00625; Guanylate_kin; 1.
DR   Pfam; PF00595; PDZ; 3.
DR   Pfam; PF07653; SH3_2; 1.
DR   SMART; SM00072; GuKc; 1.
DR   SMART; SM00228; PDZ; 3.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 3.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR   PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR   PROSITE; PS50106; PDZ; 3.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          28..102
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          172..259
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          321..402
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          436..506
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          586..761
FT                   /note="Guanylate kinase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50052"
FT   REGION          120..151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          488..539
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        493..512
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        513..539
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   773 AA;  85551 MW;  1356F89BC96B5760 CRC64;
     MLSLVNFDEE AWRNEDVEGQ LIPFPSTTIK GGIDQPQEGG DSHIVVTQIS QGGAVATDGR
     LREGDILIKI NNVDTTRVSH ETAVNALRDS GNVVKLSFKR RKGLFANDFS SLGRYNTTTR
     SSLGQGVQPT PSTYVPSHQP PSVPSHTSLT NNPITRRLSE VDRIMRMPGV RQLTLNKGGA
     GLGFSIAGGV QNEHHPGDDG IYITKIIEGG AAYYDQRLQV GDLILCVDET PLEHVSHEYA
     VQTLKATSNI VRLLYISDPH PEFTRNLVAL EDSTNRLMEG NSLRNSTSAQ NLSGSQSHLM
     GGDNYRYGTV PASDVPTGDR QVTLLKKSQG LGFNIVGGEN GEPIFISAVA PGGVADLSNN
     VKPGDLLLGV NGMSLRGADH QEAARCLKEA QSPVTLTLSY KPFEYENFKK QIENLRIDLA
     KNVGTMSQDG AFRPSSGHFY VKALFDHDAK EPGPNSMRNL AFKHGDILHV KNSSDDEYWS
     ASLVGPSGEE YDEGLIPSKK RVERKERQRR KQVNFSQGSG SLTRSHGSQG HLDNRRGSRT
     QLSFSRKFPF VKSTERLHEL AELEVSSNED PVFSYKRVES VPIDYVRPVI ILGAMKERIT
     DALVVQNPDR FASCVPHTSR PPRDNEVNGR DYYFVSKQQM DEDIKNKQFI EAGQFQNNLY
     GTSIYSVKQV AASGKHCILD VSGNAVQRLQ ETAHIYPVVL FIRPRHWKQI AAWGQDIPDE
     EAQSMYERAI KVESKFGDLF TTVISAETPE EVMARVYSAI DENARSQIWI PSQ
//