ID   A0A1I8CRZ9_9BILA        Unreviewed;       586 AA.
AC   A0A1I8CRZ9;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=PBPe domain-containing protein {ECO:0000313|WBParaSite:RSKR_0000784000.1};
OS   Rhabditophanes sp. KR3021.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Alloionematidae;
OC   Rhabditophanes.
OX   NCBI_TaxID=114890 {ECO:0000313|Proteomes:UP000095286, ECO:0000313|WBParaSite:RSKR_0000784000.1};
RN   [1] {ECO:0000313|WBParaSite:RSKR_0000784000.1}
RP   IDENTIFICATION.
RC   STRAIN=KR3021 {ECO:0000313|WBParaSite:RSKR_0000784000.1};
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC       family. {ECO:0000256|ARBA:ARBA00008685}.
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DR   AlphaFoldDB; A0A1I8CRZ9; -.
DR   WBParaSite; RSKR_0000784000.1; RSKR_0000784000.1; RSKR_0000784000.
DR   Proteomes; UP000095286; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   CDD; cd13717; PBP2_iGluR_putative; 1.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR   InterPro; IPR019594; Glu/Gly-bd.
DR   InterPro; IPR001508; Iono_Glu_rcpt_met.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   PANTHER; PTHR18966:SF411; IONOTROPIC RECEPTOR 25A; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR   PRINTS; PR00177; NMDARECEPTOR.
DR   SMART; SM00918; Lig_chan-Glu_bd; 1.
DR   SMART; SM00079; PBPe; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        280..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        499..520
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          77..474
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00079"
FT   DOMAIN          87..148
FT                   /note="Ionotropic glutamate receptor L-glutamate and
FT                   glycine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00918"
SQ   SEQUENCE   586 AA;  67130 MW;  5F8F088C6DAB6F7B CRC64;
     MINLSTIDNP NYGKYIGGID GKENILYQNV KVRIYKIVRR LDLAEGNMIK YLGNWSLTQN
     ISTFYGSLTV DVYLLKTYRV VTIIQPPFTQ WGKHESGDLF LEGYCIDLLS FIQNDLKINV
     ELYLDEEGRF GSIDENGVWN GVVGDLVIGN ADFAISPLSV MAERETDIDY TVPYYDLVGT
     AILMKKTVVD NSLFKFLQVL EWPVWLAILC AYVLTSLLLW LFDRISPYSY TNMIKKNNEM
     LVRRQFSMKE CFWFCMTSLT PQGGGEVPLN ISGRFISATW WVFGFIIIAT YTANLAAFLT
     VSRLEQPISS LDDLANQYKI EYAPIKGGSS ELYFRRMAAI EQKFYNIWKE MSLNESLNTM
     DRARLAVWDY PVSDKFSNLW KIMQESKLPE NTEKAIERVL TSENGFAFIG DAMEIRYAVL
     TNCDLQQIGQ EFSRKPYALG VQANHPLKDK LSTSILRLLN QRKLEFLKEK WWVQNPQKAQ
     CTTSDGDANG ITIENIGGVF IVIFVGIVLS IIMLIIEFYY HHHKQATIKR VNTTQSQGAM
     QISHSDYSTT SNIPNSPVTE EVEVMQLETL TLRRNTIQVI EEVTKF
//