ID   A0A1I8CTC8_9BILA        Unreviewed;       565 AA.
AC   A0A1I8CTC8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=UEV domain-containing protein {ECO:0000313|WBParaSite:RSKR_0000806500.1};
OS   Rhabditophanes sp. KR3021.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Alloionematidae;
OC   Rhabditophanes.
OX   NCBI_TaxID=114890 {ECO:0000313|Proteomes:UP000095286, ECO:0000313|WBParaSite:RSKR_0000806500.1};
RN   [1] {ECO:0000313|WBParaSite:RSKR_0000806500.1}
RP   IDENTIFICATION.
RC   STRAIN=KR3021 {ECO:0000313|WBParaSite:RSKR_0000806500.1};
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UEV
CC       subfamily. {ECO:0000256|ARBA:ARBA00009594}.
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DR   AlphaFoldDB; A0A1I8CTC8; -.
DR   WBParaSite; RSKR_0000806500.1; RSKR_0000806500.1; RSKR_0000806500.
DR   Proteomes; UP000095286; Unplaced.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd01871; Rac1_like; 1.
DR   Gene3D; 6.10.140.820; -; 1.
DR   Gene3D; 6.10.250.370; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR   InterPro; IPR037202; ESCRT_assembly_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR017916; SB_dom.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   InterPro; IPR003578; Small_GTPase_Rho.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   InterPro; IPR008883; UEV_N.
DR   NCBIfam; TIGR00231; small_GTP; 1.
DR   PANTHER; PTHR24072:SF359; RAS-RELATED PROTEIN RAC1-RELATED; 1.
DR   PANTHER; PTHR24072; RHO FAMILY GTPASE; 1.
DR   Pfam; PF00071; Ras; 1.
DR   Pfam; PF05743; UEV; 1.
DR   Pfam; PF09454; Vps23_core; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00175; RAB; 1.
DR   SMART; SM00173; RAS; 1.
DR   SMART; SM00174; RHO; 1.
DR   SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF54495; UBC-like; 1.
DR   PROSITE; PS51419; RAB; 1.
DR   PROSITE; PS51421; RAS; 1.
DR   PROSITE; PS51420; RHO; 1.
DR   PROSITE; PS51322; UEV; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          2..145
FT                   /note="UEV"
FT                   /evidence="ECO:0000259|PROSITE:PS51322"
FT   REGION          153..202
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        153..167
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..202
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   565 AA;  63365 MW;  AFD6D682AFA05911 CRC64;
     MSSDTVRSNL NKVGASYSDR AATDINRALS SYAHLKDDVH QFTYPNGKTK TVVRLKGTIP
     VVYKANTYHI PIAIYLDQKH PYTAPHCFVV PTADMEIKES SIVDRTGKIY MPYLQEWKYP
     SHSLYELLQM MCLKFRDGCP VYAKRVAPAR PAPPLPSNSP YPVGPTSMPM PSQTNTPFNN
     NPPYPTFGSG SGFSTPTPGP KEQYSNDGIS DEELKISLLS AIEDSLKKKL VFKLGGVYAE
     VAAMKDNLEI LKQGQTTLQE NFSEMCSEQE TLDRVLSELK EKRNEIAQVL QSNSGDKIKN
     LKASSDWIDE AIKPATPIHD QIVRCYVADC AYDDMMYYLS QALKKGNITL SCYTSKFKLN
     QIIITDLDFS QTHTMQAIKC VVVGDGAVGK TCLLISYTTN AFPGEYIPTV FDNYSANVMV
     DGRPINLGLW DTAGQEDYDR LRPLSYPQTD AFLLCFSLVN PASFENVRAK WYPEVSHHCP
     DTPIILVGTK LDLREDRETI EKLNERRLAP ITQQQGNRMA QEIKAVKYLE CSALTQVGLK
     SVFDEAIMAV LRPVKKRKKR ACTIF
//