ID   A0A1I8D3D4_9BILA        Unreviewed;       893 AA.
AC   A0A1I8D3D4;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Nuclear receptor domain-containing protein {ECO:0000313|WBParaSite:RSKR_0001067100.1};
OS   Rhabditophanes sp. KR3021.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Alloionematidae;
OC   Rhabditophanes.
OX   NCBI_TaxID=114890 {ECO:0000313|Proteomes:UP000095286, ECO:0000313|WBParaSite:RSKR_0001067100.1};
RN   [1] {ECO:0000313|WBParaSite:RSKR_0001067100.1}
RP   IDENTIFICATION.
RC   STRAIN=KR3021 {ECO:0000313|WBParaSite:RSKR_0001067100.1};
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A1I8D3D4; -.
DR   WBParaSite; RSKR_0001067100.1; RSKR_0001067100.1; RSKR_0001067100.
DR   Proteomes; UP000095286; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd01040; Mb-like; 1.
DR   Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR   Gene3D; 1.10.490.10; Globins; 1.
DR   Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR044399; Mb-like_M.
DR   InterPro; IPR035500; NHR-like_dom_sf.
DR   InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR   InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR   InterPro; IPR001628; Znf_hrmn_rcpt.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   PANTHER; PTHR48092; KNIRPS-RELATED PROTEIN-RELATED; 1.
DR   PANTHER; PTHR48092:SF18; NUCLEAR RECEPTOR SUBFAMILY 6 GROUP A MEMBER 1; 1.
DR   Pfam; PF00105; zf-C4; 1.
DR   PRINTS; PR00398; STRDHORMONER.
DR   PRINTS; PR00047; STROIDFINGER.
DR   SMART; SM00430; HOLI; 1.
DR   SMART; SM00399; ZnF_C4; 1.
DR   SUPFAM; SSF46458; Globin-like; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR   PROSITE; PS51843; NR_LBD; 1.
DR   PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR   PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          386..462
FT                   /note="Nuclear receptor"
FT                   /evidence="ECO:0000259|PROSITE:PS51030"
FT   DOMAIN          551..887
FT                   /note="NR LBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51843"
FT   REGION          322..341
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          356..381
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        322..337
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   893 AA;  98900 MW;  EACF03CA533D34F7 CRC64;
     MYTPRSSSKG DVNELHSDYL HFMAPSNMMV PRKSSYQHAS PHHNVVKKSS TKLSTPALIM
     TSSFNCSNTN VSTIYGNEDK TTINSSPGRA NNCLGPPKPL RRCRSATPGT GSPFNKNPAH
     LTVEAQALIK KSWRRVPKNT LGKVIYLKMV DKHPELKTLL SSDEGCVDRH LKYFINMIQC
     VVDSCHDMGN ALLPWLSLLG SGHSGFAIKA KHWDAFSEAL LCAVNQWILS GKDHKETVRA
     WMKVSCFLAD VLGNASRSGA VSNPRLQLLT LLPPSPSSSL HSLPSPSVYH QTSEPIQLKT
     ELSTSPLTKL ASLTKHLKQI SESKIKTPKQ SPHPANPTKD KFSWITHYGV TVHESTGEPT
     YINHNNQAED DDKSPKSQDT TSPSGKFLCR ICHDNSTGVH YGIFTCEGCK GFFKRTVQNK
     RVYSCVSGSA CCPMTKEQRN RCQFCRFQTC LQQGMVLEAV REDRMPGGRN NSAIYNSYKL
     KYKKTRKAQT KVKGSERSSI MNNNEDFEDV ASINEGSSGI NKWMDAAVSP TNTSSSISCS
     LSPSTITRRL PAAPSVESVC DAESIQRFKA TPTCRNLIHE MMEIDSLDTL INLKGLRIAS
     QNALLNQSEE VIPACQRLSR IGDEIVEQLV DWTKNLPFYN DLPVEIHTHL LTQRWAELVL
     LSACYYAISN CSPISEYTRS EGLLPTNSPL SQSSSSSVTS SAGSPVHFNN ILGNRLTEGH
     DEISFDDVNV NLHLLKERLS KVMHKDIPLE HVVREAGPLV EKFTSLLNSF SKLHITHEAY
     VCLKAITLLH YAPPTDALAL LTEQNEAKNG KTPSSQIKKV STIQDQFVKA LQIHLSQCED
     GPRLTDILTW LPMLHSASSV LLHSKMFYVP FLICKSPKSE SLVNSESGSD SEA
//