ID   A0A1I8EBW7_WUCBA        Unreviewed;       642 AA.
AC   A0A1I8EBW7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=CASPASE_P20 domain-containing protein {ECO:0000313|WBParaSite:maker-PairedContig_1331-snap-gene-3.22-mRNA-1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|WBParaSite:maker-PairedContig_1331-snap-gene-3.22-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-PairedContig_1331-snap-gene-3.22-mRNA-1}
RP   IDENTIFICATION.
RC   STRAIN=pt0022
RC   {ECO:0000313|WBParaSite:maker-PairedContig_1331-snap-gene-3.22-mRNA-1};
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase C14A family.
CC       {ECO:0000256|ARBA:ARBA00010134}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A1I8EBW7; -.
DR   STRING; 6293.A0A1I8EBW7; -.
DR   WBParaSite; maker-PairedContig_1331-snap-gene-3.22-mRNA-1; maker-PairedContig_1331-snap-gene-3.22-mRNA-1; maker-PairedContig_1331-snap-gene-3.22.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR029030; Caspase-like_dom_sf.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR011600; Pept_C14_caspase.
DR   InterPro; IPR001309; Pept_C14_p20.
DR   InterPro; IPR015917; Pept_C14A.
DR   PANTHER; PTHR22576:SF37; MALT1 PARACASPASE HOMOLOG; 1.
DR   PANTHER; PTHR22576; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE; 1.
DR   Pfam; PF00656; Peptidase_C14; 1.
DR   SMART; SM00115; CASc; 1.
DR   SUPFAM; SSF52129; Caspase-like; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   PROSITE; PS50208; CASPASE_P20; 1.
PE   3: Inferred from homology;
FT   DOMAIN          260..388
FT                   /note="Caspase family p20"
FT                   /evidence="ECO:0000259|PROSITE:PS50208"
SQ   SEQUENCE   642 AA;  72317 MW;  7083D9AEDFC2A836 CRC64;
     MSSVVSLQGY ELSTNLAELP SGLHWRLASS LNFQTVWMKV IGDSTSSPFS LSVSEYDRIL
     RSENQGSSLL YLWGNRGQNV RHLLLRLQSF SKMHGTSLDG PQLALRRKFV PVKWSADEQI
     TVKVMGVDNC MLQLFCHARG FPWPRFQWME DDKDIDCSNG KALIVSRCRC RKGLMYRCRI
     WNEIEEGFEY STFYRRPGKS FHSKLITNPV DLSLFITASA TVDTCERCTT YKNLNLSTDF
     SKTVQNEGNI GGWNAELIAT DKVALIIGNC NYINLPSLVT PHCDAEMFAE SLQNLGFKTV
     ALGDLNLAEM HFFIKEYRKL LGDGVYAVFY FVGHGFEKNG KNYLLAVDAP SVDCRMTECI
     SVEWILSVFE DSHPALNLIL LDVCRKNVKC VGTLGCLDDA DIEQIPKIAR NTVCGYATSS
     GVSAFEVHGE RNGVFMKHLL QHIADEATVL EMLTKTFQEI SKDTRICDVQ IPELKSNLVL
     PRGLRDPLVC YGHTASFNCH TLYWRYMHEL PSPINVQFAD QNMLVIIWYD YVGHFTNKVY
     IFSSVNDLSD KNSAEGLKPL PTKFSHVAHL RFPKHVDVSA ERIIEDGNDG VSISVMLSNL
     QRLKGAVSFS VDLASRKGDI VIASKSNLSL GHVLVTRIYR VE
//