ID   A0A1I8EHW7_WUCBA        Unreviewed;       506 AA.
AC   A0A1I8EHW7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=ShKT domain-containing protein {ECO:0000313|WBParaSite:maker-PairedContig_1993-snap-gene-0.12-mRNA-1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|WBParaSite:maker-PairedContig_1993-snap-gene-0.12-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-PairedContig_1993-snap-gene-0.12-mRNA-1}
RP   IDENTIFICATION.
RC   STRAIN=pt0022
RC   {ECO:0000313|WBParaSite:maker-PairedContig_1993-snap-gene-0.12-mRNA-1};
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01005}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A1I8EHW7; -.
DR   STRING; 6293.A0A1I8EHW7; -.
DR   WBParaSite; maker-PairedContig_1993-snap-gene-0.12-mRNA-1; maker-PairedContig_1993-snap-gene-0.12-mRNA-1; maker-PairedContig_1993-snap-gene-0.12.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.33.10; CAP; 1.
DR   InterPro; IPR014044; CAP_domain.
DR   InterPro; IPR035940; CAP_sf.
DR   InterPro; IPR001283; CRISP-related.
DR   InterPro; IPR003582; ShKT_dom.
DR   PANTHER; PTHR10334; CYSTEINE-RICH SECRETORY PROTEIN-RELATED; 1.
DR   PANTHER; PTHR10334:SF498; PEPTIDASE INHIBITOR 16; 1.
DR   Pfam; PF00188; CAP; 1.
DR   Pfam; PF01549; ShK; 1.
DR   PRINTS; PR00837; V5TPXLIKE.
DR   SMART; SM00198; SCP; 1.
DR   SMART; SM00254; ShKT; 1.
DR   SUPFAM; SSF55797; PR-1-like; 1.
DR   PROSITE; PS51670; SHKT; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        347..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        401..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          283..318
FT                   /note="ShKT"
FT                   /evidence="ECO:0000259|PROSITE:PS51670"
SQ   SEQUENCE   506 AA;  59179 MW;  78122E2DDE477D59 CRC64;
     MHAKFKEFSK KVLCKESSKN RVGPSLNLPP GTEFIQPGKA QMIYGIYHFN EEQRRQIIAI
     HNQLRAREPA SNMQELVWDQ RLADLAYGHA KRCDAWHRSA YERQGHGYSY IGENIWWSNE
     AYLRSNLQSA MLDFFNERPY YDYNTNKCMK GAQCGHYTQY VWGETCAVGC AAVHCNGIKN
     GRGINQGHII ICNYGEGGNQ FEKRPYIFGP RCSNCRCGGE CTSEGLCPPC CSGMRYPQQG
     NFLPSPVLRT QQSRKSWQNK IGVQQKHKNY QQNGNGKLYN YECRDFEPFC EHWAQNVGCY
     SKHRNFMMKR CPKTCNTCYP FFSAVNQEKM KKFRLIKTEK FVGDVHPVSY CAAVLIIIEI
     VTFGRNMVNV TALEKRIWQR IVDFLALFAL HRAIMNANIK YPGPVVTIVL ICCIIHIIFK
     KIIDPQLYEC YKSILRYEAT LQLLKDELEK NYEEYHWNNP QFCKAYLALY AAYRELRMMA
     KRDYRGEIDP NDIRWIHFDH IRNLNR
//