ID A0A1I8EJS2_WUCBA Unreviewed; 333 AA.
AC A0A1I8EJS2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA-directed RNA polymerase III subunit RPC6 {ECO:0000256|PIRNR:PIRNR028763};
DE Short=RNA polymerase III subunit C6 {ECO:0000256|PIRNR:PIRNR028763};
OS Wuchereria bancrofti.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX NCBI_TaxID=6293 {ECO:0000313|WBParaSite:maker-PairedContig_262-snap-gene-8.38-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-PairedContig_262-snap-gene-8.38-mRNA-1}
RP IDENTIFICATION.
RC STRAIN=pt0022
RC {ECO:0000313|WBParaSite:maker-PairedContig_262-snap-gene-8.38-mRNA-1};
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific peripheric component of RNA polymerase III which synthesizes
CC small RNAs, such as 5S rRNA and tRNAs. {ECO:0000256|PIRNR:PIRNR028763}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR028763}.
CC -!- SIMILARITY: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase
CC subunit family. {ECO:0000256|ARBA:ARBA00011038,
CC ECO:0000256|PIRNR:PIRNR028763}.
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DR AlphaFoldDB; A0A1I8EJS2; -.
DR STRING; 6293.A0A1I8EJS2; -.
DR WBParaSite; maker-PairedContig_262-snap-gene-8.38-mRNA-1; maker-PairedContig_262-snap-gene-8.38-mRNA-1; maker-PairedContig_262-snap-gene-8.38.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006383; P:transcription by RNA polymerase III; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR007832; RNA_pol_Rpc34.
DR InterPro; IPR016049; RNA_pol_Rpc34-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12780:SF1; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6; 1.
DR PANTHER; PTHR12780; RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED; 1.
DR Pfam; PF05158; RNA_pol_Rpc34; 1.
DR PIRSF; PIRSF028763; RNA_pol_Rpc34; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|PIRNR:PIRNR028763};
KW Nucleus {ECO:0000256|PIRNR:PIRNR028763};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR028763}.
SQ SEQUENCE 333 AA; 37131 MW; 203C9738D9B879AC CRC64;
MRNCEVILRT SVPHDFSSND GNAFCTESVT NRPNLINMVK EEEEEEASAS QASVLAVLAS
NEDGLSNEDL MKRTTGMDVK ARGEAVNALL SSGKIEMLPG HTSAAFILRL RKGTQIADAT
HEEQLIYSLI EESGKKGIWI RDIRDRTGLS QTQMRKVLKV LEQRKLVKSI KAVGTTKKCY
MLYDMVADES LTGGTFYSDQ QLDSQFVETL AHICVAMLQS KRKLSEDNHK NDPSAAREFA
FVRSTEVAQF IREKGVCRVQ LSVVDIESIL SVALLDGFIE RRADGMYRAL TAKMTRCAPS
LCPCIHCPIQ ADCKPGHIIS PQNCEYFVNW LGW
//
