ID   A0A1I8EUT7_WUCBA        Unreviewed;       314 AA.
AC   A0A1I8EUT7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=PAP2_C domain-containing protein {ECO:0000313|WBParaSite:maker-PairedContig_5379-snap-gene-2.22-mRNA-1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|WBParaSite:maker-PairedContig_5379-snap-gene-2.22-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-PairedContig_5379-snap-gene-2.22-mRNA-1}
RP   IDENTIFICATION.
RC   STRAIN=pt0022
RC   {ECO:0000313|WBParaSite:maker-PairedContig_5379-snap-gene-2.22-mRNA-1};
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the sphingomyelin synthase family.
CC       {ECO:0000256|ARBA:ARBA00005441}.
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DR   AlphaFoldDB; A0A1I8EUT7; -.
DR   STRING; 6293.A0A1I8EUT7; -.
DR   WBParaSite; maker-PairedContig_5379-snap-gene-2.22-mRNA-1; maker-PairedContig_5379-snap-gene-2.22-mRNA-1; maker-PairedContig_5379-snap-gene-2.22.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR045221; Sphingomyelin_synth-like.
DR   InterPro; IPR025749; Sphingomyelin_synth-like_dom.
DR   PANTHER; PTHR21290:SF23; PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 2; 1.
DR   PANTHER; PTHR21290; SPHINGOMYELIN SYNTHETASE; 1.
DR   Pfam; PF14360; PAP2_C; 1.
PE   3: Inferred from homology;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Sphingolipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        53..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        95..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        129..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          195..231
FT                   /note="Sphingomyelin synthase-like"
FT                   /evidence="ECO:0000259|Pfam:PF14360"
SQ   SEQUENCE   314 AA;  36665 MW;  653BDEEC330E0D6F CRC64;
     MRKGIERRES ETNFIRNISF NDDNSTDSEK NTEKKKRAQE SLITYRPEYL KTFICFLALL
     VSLILNQLVI CLAHDITSRD ALPDLVFTLV PEQEWALAVG DMLTCIAGIL ALGFIAVFHR
     YRFIVLRRLI FTITVLYTFR AICLSVTHIP ASYQNNYHKC AKPNHQATIL SVLKRFAQHS
     FKLGLQISES DKLICGDLLF SGHTIFVSTT TFYFNHYSPH SIWPLSLYHS FILLPHHVRI
     QTRTYRRLLL FWTMYELEVN VPSGRLENEI EWPLPWPKCL KRCVRNWNRR EIETMAGRIA
     EKLDAHCVKT HFSA
//