ID   A0A1I8EXV4_WUCBA        Unreviewed;      1300 AA.
AC   A0A1I8EXV4;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=TIP120 domain-containing protein {ECO:0000313|WBParaSite:maker-PairedContig_6295-snap-gene-0.14-mRNA-1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|WBParaSite:maker-PairedContig_6295-snap-gene-0.14-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-PairedContig_6295-snap-gene-0.14-mRNA-1}
RP   IDENTIFICATION.
RC   STRAIN=pt0022
RC   {ECO:0000313|WBParaSite:maker-PairedContig_6295-snap-gene-0.14-mRNA-1};
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the CAND family.
CC       {ECO:0000256|ARBA:ARBA00007657}.
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DR   STRING; 6293.A0A1I8EXV4; -.
DR   WBParaSite; maker-PairedContig_6295-snap-gene-0.14-mRNA-1; maker-PairedContig_6295-snap-gene-0.14-mRNA-1; maker-PairedContig_6295-snap-gene-0.14.
DR   GO; GO:0010265; P:SCF complex assembly; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039852; CAND1/CAND2.
DR   InterPro; IPR013932; TATA-bd_TIP120.
DR   PANTHER; PTHR12696:SF0; CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1; 1.
DR   PANTHER; PTHR12696; TIP120; 1.
DR   Pfam; PF08623; TIP120; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1147..1257
FT                   /note="TATA-binding protein interacting (TIP20)"
FT                   /evidence="ECO:0000259|Pfam:PF08623"
FT   REGION          357..378
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        362..376
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1300 AA;  145814 MW;  C7CC6D9B1DD792AA CRC64;
     METQDTENQK ASLNGFALNT IRPRLNSEKM PFQIASLLEK MSSTDKDYRF MATNDLIVEL
     QNDSIKLDDE SERRVVNMVV KLLEDKNGEV QNLAVKCLGP LVHKVKDTQA QAIFSHLCET
     MINGDEKLRD VSSIALKTAV AELPAASSPL TVAVIKLLVP PLKDALCKSF SVLFLLVFIF
     FTNYCSVNPK KDRFCCFAKM INFTADTERV DISVKLEIID IISDILSRYG SLFSPYLREL
     QEALLRQLSS DRQALRKRSI ITLSNLLALS DDTLYGETMD IIVQYLTSPG ASVMQFRTMV
     QTCQSICKTT SRRFVKHLSR LVPVLVDYTV ATEDDELRIR NFCLSLPSRN NAIHSTYCGG
     SSDSDDDDDE GNEYSDDDDM SWKVRRASAK CIEALILSRR DEIVKYLTSF GPLLISRFKE
     REDNVKWDIM HAYTALLSQI RNLIPNFSAI CVPEENGNVE KNACGDAETI TVKGGVLLRN
     AVSMEQLETL QALDSQIPLL VRAVSRLLNT KALKTKQYCF VLLTHLLRAY PGALGDEILH
     LTAGVSNAMN DRSLNTNMKI DTLTFLSGAL CTHSPEKLHA YMDVLVPLIV RAVSEQFYKV
     SAEALTVTTS LIRVLRPVAS ERGNFDYSPY VDSIYEAIIG KLKATDIDQE VKEKAVTAAG
     LLVATFGDFL KEKLPTCLPI FLDRLRNEMT RLVTVKALTV IVNSPLSISL HSILSDVLLL
     LAEYLRKNHR TLKISTLNLL DSLVTNYKYG SLDGGEMMRV IQETPALISE LDLQISQLTL
     TYLSHIVVAQ PLIISCSLPE IFVAYVNLLQ SSLLQGATLT ASLNFVLAVV QAEIPQKPSF
     EELLDQLTAP VYDNISLHRQ AYRSISACTA VVASASGQQN RCCNLAKKLS EQIMSNDTTD
     GVRLFSLLAI GELGCTCPRT FDKFSPKPEE LLVNAFNTTS EEMKTAASYA LGRLALGNLE
     KYLPFLLEQI NSQPKRQYLL LHALKEVIGS ESGDSRAIEI FRPRIEQIWP VLITHAIAVE
     EGTRNVVAEC LGKLCLVHPE QLLQRLKKCV VSPNPFMRAT AVTAVKFLIV EQWTAIDDLL
     QSSMTHFLQT VTDQDLNVRR VALIAFNSAA HNKPRLIRDL LPVFLPLLYN ETVVKKELVR
     EVEMGPMYTL LETCLERLDI FEFITHMEDG LKDQHDIKLL TYLMLARLAS LCPSQVLQRL
     DSLCEPLKTQ IQARPKANAV KQENDKQDEL RRAALRVVVA LQRIPEADRQ QQFADLLSII
     RSSSEINAVY QVTNIFIAIV DLRFYIKKDR RSNCITADFK
//