ID A0A1I8F143_9PLAT Unreviewed; 386 AA.
AC A0A1I8F143;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Nuclear receptor {ECO:0000313|WBParaSite:maker-unitig_1055-snap-gene-0.1-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-unitig_1055-snap-gene-0.1-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-unitig_1055-snap-gene-0.1-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR AlphaFoldDB; A0A1I8F143; -.
DR WBParaSite; maker-unitig_1055-snap-gene-0.1-mRNA-1; maker-unitig_1055-snap-gene-0.1-mRNA-1; maker-unitig_1055-snap-gene-0.1.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR24082; NUCLEAR HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24082:SF283; NUCLEAR HORMONE RECEPTOR HR96; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 38..114
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 149..382
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
SQ SEQUENCE 386 AA; 42825 MW; 0DC532A2716B7D11 CRC64;
QQQSQQGSGN DYDPLFSIDL LNPSSLAKLA DSGTRETIKS AASAATKALG FNFDAVSCES
CKAFFRRNAV KGVEAFKCPY SGACSIDVSN RRFCKRCRLA KCFDIGMKRE YILTEEEKLE
KRKKIDQNNC CQGPDPPADL ADRELLSDAE LQDVKFILDA YAASEAVKLP ERQGQRAVSF
DDLINFAELS VVRVIELCKQ LPEFLRLSPP DRVALMKGGA LELILLRGVI SFDPERARFL
DSGDVESAEQ DSMEGGDFLK AAGSSGYAFL QLARSLRVNL QCDRATLILL LVVCLFSADR
PGLTPEGRDS AEEAQVRYSL VLDRLLRTRL PGQEARKIYP QLLTQLAELR NLEKDFSDLA
ALTDPRVVRP LMAELLDMQE GHDGKK
//
