ID A0A1I8F427_9PLAT Unreviewed; 665 AA.
AC A0A1I8F427;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Vps39_2 domain-containing protein {ECO:0000313|WBParaSite:maker-unitig_19815-snap-gene-0.2-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-unitig_19815-snap-gene-0.2-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-unitig_19815-snap-gene-0.2-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR AlphaFoldDB; A0A1I8F427; -.
DR WBParaSite; maker-unitig_19815-snap-gene-0.2-mRNA-1; maker-unitig_19815-snap-gene-0.2-mRNA-1; maker-unitig_19815-snap-gene-0.2.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR GO; GO:0016743; F:carboxyl- or carbamoyltransferase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 3.40.50.1370; Aspartate/ornithine carbamoyltransferase; 2.
DR InterPro; IPR006132; Asp/Orn_carbamoyltranf_P-bd.
DR InterPro; IPR036901; Asp/Orn_carbamoylTrfase_sf.
DR InterPro; IPR006131; Asp_carbamoyltransf_Asp/Orn-bd.
DR InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR PANTHER; PTHR12894:SF27; TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR Pfam; PF00185; OTCace; 1.
DR Pfam; PF02729; OTCace_N; 1.
DR Pfam; PF10367; Vps39_2; 1.
DR SUPFAM; SSF53671; Aspartate/ornithine carbamoyltransferase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 626..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 211..304
FT /note="Vacuolar sorting protein 39/Transforming growth
FT factor beta receptor-associated"
FT /evidence="ECO:0000259|Pfam:PF10367"
FT DOMAIN 381..441
FT /note="Aspartate/ornithine carbamoyltransferase carbamoyl-P
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02729"
FT DOMAIN 468..592
FT /note="Aspartate/ornithine carbamoyltransferase Asp/Orn-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF00185"
FT REGION 477..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 665 AA; 74826 MW; 856D43663842BBD5 CRC64;
ELGVPYQDLI FRYSRWIIER DPKEGLRIFT AESQADTVAN FLESSAPQLL TDYLEHCVLH
CKPPDTSESL HTRLANQYRL RLEQQTEPLA VAGAPGPDLL AFLRRSRHYN AQELLARYPN
NDMLEERALL LSRLGQYELA FTILAQYLRV AGEGLSLLAE EILSQPTAET GDAADSSLAS
LQGEVYGQLI KALAGWRPCL PRPINCIYRL SRVLPLLPPA TPLADLSDYL LTSLQRLEAE
KRLLQSRRGL YHAERLQTAA AFARVRSGRV AIEEGTRCSV CQNRIGASAF ARFPSRQVTH
YGCMALFKPA MSPLQLLIKS SRSLWPLSSP PRIASRRRFI NGRLNRQVGS NLKGRHFLTL
RDYSESEIAQ LARATLLHDA LRSASTRTRV STETASSCSA VSRCVLSPQD VHLGTNESLP
DTAKVLSGFC DAVLARVYAH DSPVPSAGRC WRDFFTAYEN FGHLNGLIRI ASPAGYDPNP
ARGAGRPRAQ PPVRHPAGAH TRDPRRGGSR ADVIVTDTFV SMGREAEKER RLKEFQRVNS
SLVAHAKPRW VFMHCLPRKQ EEVTDDIFYD SKRSLVWPES HNRKWTVMSV LLNVLNDQYR
PACPCRASEH SLAPWLSCFW TRAIRMWVFL PLVIITFLFG VIRHYVTILI SAEKKAEPEQ
VSDQQ
//
