ID   A0A1I8FBZ4_9PLAT        Unreviewed;       689 AA.
AC   A0A1I8FBZ4;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=USP domain-containing protein {ECO:0000313|WBParaSite:maker-unitig_27230-snap-gene-0.2-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-unitig_27230-snap-gene-0.2-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-unitig_27230-snap-gene-0.2-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A1I8FBZ4; -.
DR   WBParaSite; maker-unitig_27230-snap-gene-0.2-mRNA-1; maker-unitig_27230-snap-gene-0.2-mRNA-1; maker-unitig_27230-snap-gene-0.2.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 2.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR018200; USP_CS.
DR   InterPro; IPR028889; USP_dom.
DR   PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   PANTHER; PTHR24006:SF888; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   Pfam; PF00443; UCH; 2.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS00973; USP_2; 1.
DR   PROSITE; PS50235; USP_3; 1.
PE   4: Predicted;
FT   DOMAIN          1..689
FT                   /note="USP"
FT                   /evidence="ECO:0000259|PROSITE:PS50235"
FT   REGION          217..267
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          317..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          490..509
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          527..583
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        317..341
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        547..583
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   689 AA;  74823 MW;  EC76F1DC3F067AF4 CRC64;
     AIPCYANAVL QVLCYTPGLY NHLRKLCYSL HRIDRLVTES MQEKLALPLS CAFVEHMFIG
     CFAMIRVERR TCRPGPRLLR ILRSMHCAFT PGEEHDAQEL LLCALDAVQP FRNSLAELAR
     GLGEQPAAGC CRCLSDSPPP PAWRRPCGCQ TSQTMTVRLK PRRAREAAAA GSDSYDAPLL
     RLDEFVDDDD LFSITAAATA AQDDGDSPFP VRHCRAHLPP PRRVSTAGAT GPASTPSRCR
     PACRRAAPLP RRTGRATAGR GSAARPDAPT PLEVVLAQPG PAAQQLRPAF GADAFKLRAA
     RRANRLIAAE SPRRPLGQQN LAVNSGGLPS ATLSPHQSHL PASAAAAQLP HPLPWPPSPP
     RLPASAAHAL RCRRGHQRRA GPTNDENFGA SPLKTAAPPA VFSVLLFWRR LVRDELGGVG
     RLRPTAAALL ASPWLSWSLL HRGAGHRRSS ASRLCGQSND CSSYTTRCME CESETVKCQP
     FSIISCPVKP HRRSPAADEP PAHRLPPAPT RLNRRFAAKP VPWNLNKPVP VNLTRTKSRD
     RTRSQSLETS PEPVPVNLTR TSPVNLTRTS PVNLTRTSPQ SDAGLRAAVS PLAFCERRSA
     DTGDDKFLLR PVQRALAGST LSRPDAGAGY SEALYKVVSS QAPCRSARRR YELYAVIIHD
     GLTISSGHYT SLVRLPEPGS GWFSFDDDL
//