ID   A0A1I8FCX7_9PLAT        Unreviewed;       436 AA.
AC   A0A1I8FCX7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Lig_chan-Glu_bd domain-containing protein {ECO:0000313|WBParaSite:maker-unitig_29666-snap-gene-0.2-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-unitig_29666-snap-gene-0.2-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-unitig_29666-snap-gene-0.2-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A1I8FCX7; -.
DR   WBParaSite; maker-unitig_29666-snap-gene-0.2-mRNA-1; maker-unitig_29666-snap-gene-0.2-mRNA-1; maker-unitig_29666-snap-gene-0.2.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   InterPro; IPR019594; Glu/Gly-bd.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   PANTHER; PTHR18966:SF422; KAINATE-TYPE IONOTROPIC GLUTAMATE RECEPTOR SUBUNIT 1D; 1.
DR   Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR   SMART; SM00918; Lig_chan-Glu_bd; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          3..61
FT                   /note="Ionotropic glutamate receptor L-glutamate and
FT                   glycine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00918"
FT   REGION          408..436
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        413..436
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   436 AA;  48211 MW;  65EF2030EFA55BD1 CRC64;
     SEGFSTKDIN GRWVGFYPEI VGELSRRLNF QATFKRVSDG RYGSYDNQTG RWDGMIGDVY
     SGDVHFAAAP LTLNAVREEF VDFSHGVLNF GLVVVAKPAK WVNTARSSGC QVFPARLRPG
     RLAGLWRGVL LTALLLHYNG RYNPAENGSA VSDELRCQNR QQRGGPPVRP ATLGNRRWRV
     WRRRISTVAP AAELPLSGPS AGFSKWPRSL AGALRQRLLV AVSSPSYAAT YSGGFLCALV
     ATEAPQLRPC SQQFQPEARQ ASLRETTGTG RLLHAGTLID LVLRDTQILG VMEAPMADFL
     REEDRLRDQS SLGDLTNDKS YAFAFAENSS LTGGSTWRFS RLKRASPAAL CGQQDGGLAA
     ARSRRLAKSA RMFPRKHPVT LNSFPGPLIL RSSNFRRKVT NESTANMSLT AAHQRRRTKE
     IERRRVVSSG LQEDFR
//