ID   A0A1I8FDU7_9PLAT        Unreviewed;       524 AA.
AC   A0A1I8FDU7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=GPS domain-containing protein {ECO:0000313|WBParaSite:maker-unitig_30014-snap-gene-0.1-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-unitig_30014-snap-gene-0.1-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-unitig_30014-snap-gene-0.1-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A1I8FDU7; -.
DR   WBParaSite; maker-unitig_30014-snap-gene-0.1-mRNA-1; maker-unitig_30014-snap-gene-0.1-mRNA-1; maker-unitig_30014-snap-gene-0.1.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR   Gene3D; 2.60.220.50; -; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR046338; GAIN_dom_sf.
DR   InterPro; IPR017981; GPCR_2-like_7TM.
DR   InterPro; IPR000832; GPCR_2_secretin-like.
DR   InterPro; IPR000203; GPS.
DR   PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR   PANTHER; PTHR12011:SF470; LATROPHILIN-LIKE PROTEIN LAT-2; 1.
DR   Pfam; PF00002; 7tm_2; 1.
DR   Pfam; PF01825; GPS; 1.
DR   SMART; SM00303; GPS; 1.
DR   PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR   PROSITE; PS50221; GPS; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        344..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        409..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        444..465
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        500..519
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          342..518
FT                   /note="G-protein coupled receptors family 2 profile 2"
FT                   /evidence="ECO:0000259|PROSITE:PS50261"
FT   REGION          138..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   524 AA;  55762 MW;  0B0730FA03F3D8F7 CRC64;
     PTCPPGSYPR LINTPVELPP SARRYICLPL AEVGGEECRK LAKAALSVYQ TEKGSCAELK
     SCNSTSVRAQ LLTKFADTQI FDSLDAVTGF ARVLSEQLPV GLNPSKPVSA AEQRNTVSDL
     LSSVSAFAPL DLWAAESTTT NPSAGGGRRS SEEAQRGLTT AADTVLRAID SLGLGLQAAA
     APAEAVYNSS GIGLSVLRLS SSAGFTAPGP GVSVKVRYSG SLASVAMVTS SVDLPHLIRW
     LRPAASDQQV VSQIVQASLF SAGGKLQSGG SALFLVRMPP RQMRRVRRSC VFVDSNGRLS
     DTGCSVVAEL SDQSRTACLC SHLTSFAVVA SPGSSWQTVE SRQLLTYICL SLSIVCLIVT
     CLAYLPLRLK SPNAESTIVT LHRVHRALCA TLIVAQLLFL VGYERVEFGF LPCQILSGLT
     VYSFLSSLLV VLPGANSALA KLKFWHYCLL SYLAPAIIVA IAAAVRRDQL IQTEADLSAD
     SDTLERPSTC WLSETYGTRW AFLGPMLAVC AINLVLFICH PSQD
//