ID A0A1I8FRH4_9PLAT Unreviewed; 727 AA.
AC A0A1I8FRH4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=Nucleoprotein TPR {ECO:0000256|ARBA:ARBA00019789};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-unitig_43692-snap-gene-0.2-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-unitig_43692-snap-gene-0.2-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TPR family. {ECO:0000256|ARBA:ARBA00005274}.
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DR AlphaFoldDB; A0A1I8FRH4; -.
DR WBParaSite; maker-unitig_43692-snap-gene-0.2-mRNA-1; maker-unitig_43692-snap-gene-0.2-mRNA-1; maker-unitig_43692-snap-gene-0.2.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0034399; C:nuclear periphery; IEA:UniProt.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProt.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR InterPro; IPR012929; TPR/MLP1.
DR PANTHER; PTHR18898:SF2; NUCLEOPROTEIN TPR; 1.
DR PANTHER; PTHR18898; NUCLEOPROTEIN TPR-RELATED; 1.
DR Pfam; PF07926; TPR_MLP1_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 23..138
FT /note="Nucleoprotein TPR/MLP1"
FT /evidence="ECO:0000259|Pfam:PF07926"
FT REGION 363..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 423..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 17..146
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 171..242
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 440..460
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..476
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 482..496
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 514..536
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 577..597
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 625..646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 727 AA; 79737 MW; 9DE165CD14716AED CRC64;
TLVSDRFKQT EEAHAMNADL RKQLHDRQQE LQAAVERRDA AVSAEDRAKA RATAEAAKAA
EAADKYQQEL LLHAADAKAM QAIRAQLAEA EKTCAEAREE TRKSRADYEK RIAALTAEAQ
RLRASKTEAE TRLTQLAAEF SDVRRRLLAA EEAGGAPAGK TGGDRRDSLA LEDRARQVAE
YQAEAARAEA SPRADELAAQ LAPLRAQLAA AATQQAEAEE SARLLTEERN RWRDRCQELL
EKTERMDADQ YKQACSERDA LQWKASKKKV DALNSDIADL NNQLEETSEK YEALTEESKT
TQDRLASVTS ERDDIDQVLA QKVKELEELA ADRDRLARTL EEQRERYKRV QEVARKYKQE
AVELRSGRDG GESELAKLNQ KSAPAEAEME QAAEAAELAE DAQLQPEAEV DQPEVAAELN
LEEFVGMMSE EAGADEAERL GEELADEPEA AAEDFAEVVH DEDENAAMRA EPPSEHGGQD
DVIVLDDEED DVDNDKEQPH EEAQEADDEA AGSANADETS QCDAPEAKNS MAQETAEPAN
MAARRAARRL RRRSGHAVSQ ASVPPQSQAS VAPQAGWRRS RRRRWRRSRR RRWRRSRQAS
VAPQSQASVP LPRRPRIEPI VWTPNSAEAE SSATSSAPTP GTAGTSTAPV GAAAAAGSAL
PAPRRGWGQQ MMRPTMAGTR GGIGSGVDRG GAVGAEEGGQ QPARLRSWSK RKPTDDSTKA
AAMSWRL
//
