ID A0A1I8FXK3_9PLAT Unreviewed; 800 AA.
AC A0A1I8FXK3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=LSDAT_euk domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0000189-snap-gene-2.5-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0000189-snap-gene-2.5-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0000189-snap-gene-2.5-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A1I8FXK3; -.
DR WBParaSite; maker-uti_cns_0000189-snap-gene-2.5-mRNA-1; maker-uti_cns_0000189-snap-gene-2.5-mRNA-1; maker-uti_cns_0000189-snap-gene-2.5.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR041491; TRPM_SLOG.
DR PANTHER; PTHR13800:SF12; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER-LIKE 2; 1.
DR PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR Pfam; PF18139; LSDAT_euk; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 76..327
FT /note="TRPM SLOG"
FT /evidence="ECO:0000259|Pfam:PF18139"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 36..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..723
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 800 AA; 88141 MW; 290436189017C6D8 CRC64;
MDFPHPGVSS TTGWGPASSA GAASIASVSA TAAASVGGGG GGSFRRQSLK QQQQQQNEEA
SKTFGEIEFS GLKQLAKFVR LDSNTPDSAL QQILGKKWDL TRPTLVINIF GGDFEKKRQL
KMIFKKGLWK AAESAGCWIV TSGFHLGIMK LTGEAVRDYT DAYGSNYMIA IGVASWNCIA
RREALEDPNI SEGSVPATYQ SEESDSSKPK ELRASDEDES PLDPNHTHYF LVDTGATDQK
KGYDCPFRTR FSHVISSWTD EENKQLKVPM CGLLIGGDRF ALEQVFYALT ETKCPIVAVK
GTAGAADVLS SAFDYLFEEE NQVDKKEEDE ETQEANFNSK MSNICQEFFN CNDYFDYTKE
IDMLRVMLKE GASLIEIFDM EEDFDLDGKM ISSLLSSAGS EGGEDQLNLK QLKICLTLNR
ADIARDKIFL ENKKWKKGDL NEYMYQALME DRHDFVKLFL EQGFSLEDFL SIYILEKLYT
DQLKRLSSKV AIFHQLWEYH RSHRRSLGRR LKEYKARQRM KRNQKQENGN SKKVKLREVG
KVIKVLVGDF YQPLYAKKDF EKNYTKSVVT AQSPVDQSTT KALVQTAQTG YLPAYFFTKS
GPGQNSGSDA AGVGGDNMPQ AVPKRRRLQA GDGSQETQLE ICEYERSPIN FSRDAIAAHH
ISSESSVTFS DGIRFIDEDD DTSDSNARGY ENPIMESSSD SPANASGSRA TQRGGAGRSL
TDDSIVRIPA APLRRRRSSL EFMEILNISP SMFDTQMPSM PSVASAGDLS LGGGGGGGGG
GGRGGGKAGG KNGIPAFSSN
//
