ID A0A1I8FZF1_9PLAT Unreviewed; 352 AA.
AC A0A1I8FZF1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Hist_deacetyl domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0000372-snap-gene-0.8-mRNA-1};
GN ORFNames=BOX15_Mlig012185g1 {ECO:0000313|EMBL:PAA89099.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0000372-snap-gene-0.8-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0000372-snap-gene-0.8-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:PAA89099.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA89099.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA89099.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; NIVC01000164; PAA89099.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I8FZF1; -.
DR STRING; 282301.A0A1I8FZF1; -.
DR WBParaSite; maker-uti_cns_0000372-snap-gene-0.8-mRNA-1; maker-uti_cns_0000372-snap-gene-0.8-mRNA-1; maker-uti_cns_0000372-snap-gene-0.8.
DR Proteomes; UP000095280; Unplaced.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0004407; F:histone deacetylase activity; IEA:InterPro.
DR CDD; cd09993; HDAC_classIV; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR044150; HDAC_classIV.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF33; HISTONE DEACETYLASE 11; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 51..338
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
SQ SEQUENCE 352 AA; 38065 MW; 1E3CE8F748BC43E8 CRC64;
MASNASEAGA GPAKESTSYL SPLYISVPES SWPIVYHPSY NISFAGLEKL HPFDSGKWGK
IVGFLIEAGL LQQHQLVQPL EAQEADLLKV HTADYLNSLK WSANVARVTE VGLVAMLPNF
IVQRKVLKPF RFHVGGTVLA AKLALDRGWA INIGGGFHHC CGYRGGGFCA YADITMAVKF
LQRGYAGPES QIQRAMIVDL DAHQGNGHER DFLGDKTVFI LDAYNVQIYP GDNAAKPAIS
CSVDLTAGVG DNAYLDEVSK ALEESLNGSF QPQLVLYNAG TDIMDGDPLG LMRITPNGII
RRDELVFRAC RTRGIPVVMV TSGGYQRSNA RVIADSILNL RDKGLIEGPT AG
//
