ID A0A1I8G4B4_9PLAT Unreviewed; 305 AA.
AC A0A1I8G4B4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=KCNQ_channel domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0000752-snap-gene-0.11-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0000752-snap-gene-0.11-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0000752-snap-gene-0.11-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A1I8G4B4; -.
DR WBParaSite; maker-uti_cns_0000752-snap-gene-0.11-mRNA-1; maker-uti_cns_0000752-snap-gene-0.11-mRNA-1; maker-uti_cns_0000752-snap-gene-0.11.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR Gene3D; 6.10.140.1910; -; 1.
DR InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR PANTHER; PTHR47735:SF9; POTASSIUM VOLTAGE-GATED CHANNEL KQT-LIKE SUBFAMILY, INVERTEBRATE; 1.
DR PANTHER; PTHR47735; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4; 1.
DR Pfam; PF03520; KCNQ_channel; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692}.
FT DOMAIN 30..137
FT /note="Potassium channel voltage dependent KCNQ C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03520"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 107..141
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..305
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 305 AA; 34186 MW; 8DC83F3775504ABE CRC64;
MTEAAATSAA NLEQQPSLTS IAHDEEETPM KLTEVHKTAI RVIRRIKYFV ARKKFREALR
PYDVKDVIEQ YSAGHVDMLA RIKVLQFRLD QILGRQGSKD KDAYESKVSL ASRIVKVERS
MEDVERKLEL LIDMYKEDRR AAFPKKISPV PVGPPKSPPP RRRQRRWRRG DGDAELHRQR
GQRRQRVFQQ PGVSSLRAAS KEPPKPALRP AARAGLRARA AGSQASDLGP RQPKRVTYHH
PPDTALPAVA GRTTAVCEAQ VHNAFATNPS APSPPPPPLK SLIDFDDDED DEECSGKADD
TDEDD
//
