ID   A0A1I8G5J6_9PLAT        Unreviewed;       433 AA.
AC   A0A1I8G5J6;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   22-FEB-2023, entry version 20.
DE   SubName: Full=EGF-like domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0000813-snap-gene-0.8-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0000813-snap-gene-0.8-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0000813-snap-gene-0.8-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR   AlphaFoldDB; A0A1I8G5J6; -.
DR   WBParaSite; maker-uti_cns_0000813-snap-gene-0.8-mRNA-1; maker-uti_cns_0000813-snap-gene-0.8-mRNA-1; maker-uti_cns_0000813-snap-gene-0.8.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.10.25.10; Laminin; 1.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR013111; EGF_extracell.
DR   Pfam; PF07974; EGF_2; 1.
DR   SUPFAM; SSF57196; EGF/Laminin; 1.
DR   PROSITE; PS00022; EGF_1; 1.
DR   PROSITE; PS01186; EGF_2; 1.
DR   PROSITE; PS50026; EGF_3; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        155..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          80..113
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   REGION          184..317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        206..220
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        221..235
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        264..297
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        103..112
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ   SEQUENCE   433 AA;  45004 MW;  524FA341090D1093 CRC64;
     AQKSSSVTCK FLRPNVPVAN GTLCQLNGAE PGACLAGQCR PMSEFVAATS RSGGVADKCR
     HSDSDIAVVD DDSSSSTSPS TASTAGAACL ERGVCTSAGD CLCRPGWSGP ACSRAAAVAA
     ATPLQTVYWR MRDSSNGMGA GANGSGKPDP TVTTVILIGI VGAVALALLL VIAVVVFCCR
     SRGSSSSSAN GHPIGGGGPG GGSNGRGKHR KREDLRRNNL SDGQDFSSYP QRTITFAPSG
     RGGGGGGSSA GDASPVSYVG SGYKRSVESP QSNQFLLQQQ QQQQQQQQQQ QLQQLAGASP
     PPLFAPSAEP PPPEKGILRN KEVGELQEMA NLLNQQIGLS GSLSTLDDEY DEDLHSRYGL
     DTKSGHPGLA SSKTPVIVCN SSNQTDPTLF TLPEEKACLQ GDKDSCGGFD VLPESDRYQM
     PLLQQHHLQQ QQQ
//