ID A0A1I8GCU0_9PLAT Unreviewed; 847 AA.
AC A0A1I8GCU0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=EGF-like domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0001575-snap-gene-0.6-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0001575-snap-gene-0.6-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0001575-snap-gene-0.6-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; A0A1I8GCU0; -.
DR WBParaSite; maker-uti_cns_0001575-snap-gene-0.6-mRNA-1; maker-uti_cns_0001575-snap-gene-0.6-mRNA-1; maker-uti_cns_0001575-snap-gene-0.6.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 12.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR24044:SF417; EGF-LIKE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR24044; NOTCH LIGAND FAMILY MEMBER; 1.
DR Pfam; PF07645; EGF_CA; 6.
DR Pfam; PF12661; hEGF; 3.
DR SMART; SM00181; EGF; 16.
DR SMART; SM00179; EGF_CA; 6.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 4.
DR PROSITE; PS00022; EGF_1; 5.
DR PROSITE; PS01186; EGF_2; 8.
DR PROSITE; PS50026; EGF_3; 9.
DR PROSITE; PS01187; EGF_CA; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 182..213
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 303..345
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 456..496
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 499..535
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 583..622
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 624..663
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 666..697
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 745..781
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 783..822
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 186..196
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 203..212
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 525..534
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 593..610
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 612..621
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 670..680
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 687..696
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 749..759
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 771..780
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 787..797
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 847 AA; 89285 MW; DCD74FC07D8589A9 CRC64;
SADSLEPPRW SVGLEAAPED RGLWRRLAEI YNRRTAADRD EVEVEAGESP TVGTADPVLL
RRQEAALIPR DGATIVDADS IPPNYFEVSE AAAAAAAAAA ATTSTPAPGY FNGEPPDKNL
GIGSEVPASV DPAEAMAACQ PPWCYPAKCT SSNPNCPPIV CPPGTEAKLR PDGSGVYQCV
ATTPPCVPAC KNGGVCTKSR CVCPVGFTGD YCESVNKRQC RLLTGRICDY GCRQVGTEYR
CLCPPWISAP PGGFGPGSNL TCVPADPNGA PDEPCRAPCL NGVCRGGACV CRPGWRGDDC
GRDVDECADE WLNRCMYRCA NTIGSFRCEC PPGYRLSPLD GTSCEPLVCP PDCGPPGGRC
VDGRCACQPG WTGDSCRRDV DECASNHADG RPAAARRCAP GSFRCRCPPG QRLGSDGRSC
APSNSCEPAC RPDTGACVNG SCACRSGWSG PDCASDTDEC ALGFHACRHG CANTPGSFRC
LCPPGYRLAA DGRNCRPDDP RACSDRLRPC QNGGACDSGS RRCRCPPGFY GDFCQKAAPT
TTTTSTTTTS AAPTTVRPGE ECRPPCQHGR CIRGGCVCDS GFEGAACQIR FRCTGSADCS
RGWCGADGRC VCLAGWRGLR CDMDFNECDL SPAPCEHSCH NLPGTFRCTC DPGFNVGTNG
SCVWAGDPSC PRGCRNGGRC RSGRCRCAPG YRGPTCSADV DECAMERSVH GCEFACYNTR
GSWECRCPPG YTRLSDRRTC RLSPPDSRCQ PPCLNGGVCR LAASGIGNCA CQRGFAGPDC
GSDVDECALY RPCQHQCVNT VGSYTCRCPA GQLLRFDGVR CITPEEAAGR PDLLYRGTGV
KGPTVAP
//
