ID   A0A1I8GFF7_9PLAT        Unreviewed;       527 AA.
AC   A0A1I8GFF7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=tRNA (guanine(10)-N2)-methyltransferase homolog {ECO:0000256|ARBA:ARBA00013960};
DE   AltName: Full=tRNA guanosine-2'-O-methyltransferase TRM11 homolog {ECO:0000256|ARBA:ARBA00032604};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0001677-snap-gene-0.25-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0001677-snap-gene-0.25-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A1I8GFF7; -.
DR   WBParaSite; maker-uti_cns_0001677-snap-gene-0.25-mRNA-1; maker-uti_cns_0001677-snap-gene-0.25-mRNA-1; maker-uti_cns_0001677-snap-gene-0.25.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR000241; RlmKL-like_Mtase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR   PANTHER; PTHR13370:SF3; TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG; 1.
DR   Pfam; PF01170; UPF0020; 1.
DR   PIRSF; PIRSF017259; tRNA_mtfrase_TRM11; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022555};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT   DOMAIN          266..399
FT                   /note="UPF0020"
FT                   /evidence="ECO:0000259|Pfam:PF01170"
FT   REGION          395..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   527 AA;  59020 MW;  C886F1C569587B1C CRC64;
     FQSMETITSP TTTEAREYIL LYASCEYAQF RFAEFVSLAG LFDCRFGVVF TGIDRERQLI
     ANYSQQQPIW SDELFSDTPT NAGVHDWTGV AAEASIGNNK LQLCSTWWRS RSVVCILCED
     EIKLRQVVKR SALIKSLLRV WQSTSCLLTM LNHVTNGELA PYLAEASSGF DNGAWTRWRM
     CIELVNVSAA MDFKVGIVDQ FGEAGLDMPG QVDLKKPEFE LYYLEHWRYD LTAGAVTDKT
     PVRVYLAPKL CSGQSRAALH NLSLSRRIFI GNTSMNVQLA FIMCNLARVS PGQLVVDPFV
     GSGSILVSAG YLGAYCLGQD VDYNIVFGLG KSTKAEMRRQ KRTEDERLSA NFAQYGISNR
     FVDCLVGDAS QHVGLWRHSA LFDTVLTDPP YGIRERSRKV KRDPDGGPKK LDENYFPPKE
     HYSLGDSVSD LLGFCAMRLV PGGRCVYWFP VIQSEYKGAD SLPVHPCLQL IASVELPMTH
     RTARVMVCVQ RLPMVDTPEL VAMASNGATI VNHDHHQLRS SHYSRKK
//