ID   A0A1I8GFY9_9PLAT        Unreviewed;       661 AA.
AC   A0A1I8GFY9;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   03-MAY-2023, entry version 24.
DE   SubName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0001755-snap-gene-0.3-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0001755-snap-gene-0.3-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0001755-snap-gene-0.3-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the hook family.
CC       {ECO:0000256|ARBA:ARBA00006946}.
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DR   AlphaFoldDB; A0A1I8GFY9; -.
DR   WBParaSite; maker-uti_cns_0001755-snap-gene-0.3-mRNA-1; maker-uti_cns_0001755-snap-gene-0.3-mRNA-1; maker-uti_cns_0001755-snap-gene-0.3.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR   GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IEA:InterPro.
DR   CDD; cd22222; HkD_Hook; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR008636; Hook_C.
DR   InterPro; IPR043936; HOOK_N.
DR   PANTHER; PTHR18947; HOOK PROTEINS; 1.
DR   PANTHER; PTHR18947:SF39; PROTEIN HOOK; 1.
DR   Pfam; PF05622; HOOK; 2.
DR   Pfam; PF19047; HOOK_N; 1.
DR   SUPFAM; SSF116907; Hook domain; 1.
DR   PROSITE; PS50021; CH; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701}.
FT   DOMAIN          4..120
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   REGION          613..661
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          179..410
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          466..591
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   661 AA;  74839 MW;  8C9BD31C9DBBAD5B CRC64;
     MNKADLFENL LKWLQTFECA SGVSSALELS DGVIIAKTLH TISSDCFSED WLSKIKPESG
     SNWRLKVSNL KKIVKAVRDF YSDCLDMHIN DFETPDINSI GESASPDELG ALLQLVLGCA
     VSCADKEKYI QLIMGMEEQF QQSIMLAIKD LMDRPRAESD VDEKLKKALE DCYSAVQAKE
     EMSQRCHELD YQVSALQEER TSLQAEVERL TRRVESLESA QKAESGAAYR TRALEEQVEL
     MQEELCRLEA QRQEAKARAD QLEREKEDLL RQSGNLAALR DELDVLRERQ ATLAKTEAAL
     EQMRRKAEDA SELRSQLKLL QQQGEESLRR RLELEEENER LLDSRRLAES LREQLAACQA
     ELSEERKRAE RAALDLAHHV SRAETLEPEL EKLRIERDSL REANEDLEMQ VKLQADPSGK
     SLALEDDEPE FLGLPLRVKE KLLRLERDNR RLKESQESSE AGGNVVQDLR RQVSDQLTAR
     GQLEAELQRQ RQRMLELEDR AKSGAARVKE LSEQLARREE EARGAEERYK RYLERAKSVI
     RALDTRATSH GLNETEELGA LKQQLVEKDR VIEQLERAQE KSQKCREMED RLMVSAWYSL
     GMQLNQGVAG EYDLPGGGGG SPGQTFLQRQ RMAHLQRPGP QGAAGPGGGA AAAAGSVADR
     D
//