ID   A0A1I8GGM3_9PLAT        Unreviewed;      3260 AA.
AC   A0A1I8GGM3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   22-FEB-2023, entry version 19.
DE   SubName: Full=ANK_REP_REGION domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0001830-snap-gene-0.5-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0001830-snap-gene-0.5-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0001830-snap-gene-0.5-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   WBParaSite; maker-uti_cns_0001830-snap-gene-0.5-mRNA-1; maker-uti_cns_0001830-snap-gene-0.5-mRNA-1; maker-uti_cns_0001830-snap-gene-0.5.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR045329; LZTS.
DR   PANTHER; PTHR19354; ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR19354:SF2; ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED; 1.
DR   Pfam; PF06818; Fez1; 1.
DR   SMART; SM00248; ANK; 6.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   REGION          317..349
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          398..441
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          514..583
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          731..756
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          772..794
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1191..1304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1323..1369
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1537..1587
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2538..2565
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2797..2818
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2965..2984
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1406..1440
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1470..1518
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1587..1663
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        545..583
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1206..1268
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1332..1348
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1537..1559
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1561..1578
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3260 AA;  350090 MW;  15F66FA00C4B95DE CRC64;
     QQGRFKRTPV HQAATNRTSK EALRWLINEC GSEALKVTDE HGNTAVHLAS CKQDEDSLKL
     IKDCLGCLVF MVRGRHGFTT VHYAAMNVNG DASLLWFVKE LGSSCLLEKG TALDQTPLHL
     AAQHQGERPI DVARRSLGLS CVMQADRRRR TVVHYAAMNR RSTAALRQIV AQLGPECLKQ
     KDADGSMCLH LAAQYQGLES MALIWDCLGA TAFKLEGQNS RTMVHYAAEN DQKKELISWI
     VRKLGHQCLL ISDSEGGISP FALGLAARSL QFEQQHFVQR LRAAGHRPIL TCDDFDWRAA
     SGAPLARQMA RRRAWERTKS APLAVSAPQR RTAGSPRIDG FGPDPPERTL QGEQQDVLNG
     LGAVALGPDH VARQLKSPPA QDGGRALQLG PIVQGLGPDA LDGFDHRLPQ PSPLAVGQRF
     GLEDGSDRTK GRPGKSSAPP EVFFHVGHQT AEVGEPLAAC EPGRLPVCAA ARQVRWDVGR
     HSQHLGLQRV DDQTDARCHL DQPVDLALGA FNGRGQEGEV PSTLRRFSPW RRPMRLRSRK
     PSLAEGSAVR STQSSSSTKR NGASVSPCRT PDEVSNRSDR PSAVTTAARV SQYSAMTASI
     SCWGTRTKGS AALNTESNAF RKSTKTMISV DWRMRASSMT RRSARICVTV PRCGRNPFCS
     YRRYGSSTDC RRSSSSRLKS FAVQDISEIP RWSSFRVVPA FFGIGTMCAT VHSVGAGAPA
     STRFMTPVTW EATQRSRSAS TGTSSGPSAL PPDVFRANST TSSVVTGLVQ KSSSAGSGVS
     SGSAKLAGSG DAGAFTMPAK KSRNSFLRSS GCRRPGSAPR AFCAPDGPNG VVDSGLLPLV
     KKALKCVFSV ACGPPVSAES LDVEPRLPDD GVALPDRQRF LRWPHQRDRL LCSGSNGGAD
     VGILRLALVS KRADEGTREL TLHAGVQQCA IVAPWPLLWR SVELVAEPQV ADQESRSHGV
     AVGDAAALAS ANQRMIELRQ SPRGIPPACV PPPSLAARKG DQAGRGLAEL GVRGHQVQPV
     KQVLQRIGVG VLASRDKGRA LGPPRDCVQV SEHCQRVAVW HLFQLPSQEV EEGTSLLGVS
     SGGCIRAEQP DAAGAQSQVD PHQSRDSEMQ CTLCWRRGPI STPTPPRPRL SADVYRREPR
     LSHDRNLLHR RGVEDSCMLR RSRWSSAVVA EESFSLAPVI TADVVRLAQQ SPGGKALGPD
     EYHQYQPAPK QQQATQQSLQ RSAPGASPVS QARSGSRGSS SGRWRSQESL SEASPQLLMS
     SGNSGSSGAA GGGLMFRSVQ ADPPPRLLPS GVPPVSQPSG ACAMPHSQSA NLGSLILRPS
     AFRPVRIGNG GSSGGAFQQQ QRQHPVTPPS GDSGFVDVSG YGRRSQEPSL SRSAAVVDCD
     FDVDGDGDDR SSACAATSPS DSGLLLADYE NLLREKDNEL AELRRTMEQN ESALVRVFEE
     RQGELESRLR NEMALNARLT PAVSLGNRRL RQSEQAINDL RLQAQTHLDE LQSLKSQLRT
     AEAELRDRSG RVQQLEASLA ASRESLDAAT WELRRQRSRR ANDNDDNGVA DDDADRGAVS
     TADRSCQTDA TATSGAPKDS DSGGGGLEQR QQLLDELAAL RTQLEEQKSE FDQERAQWLE
     EKSQVLNYQK QLQMNYLQLT KRSQRLEAEA QQLSVDLETK EMHILRLSNG CSSGGSSAAG
     TLQSHSDRSL QPGHFALLAA AQFFRGQLAA DGLQQAVQLV GGQSKLGHQA GGLGGEAVQL
     KAEDDHVHQL LVLHDLRQRP LLLSRAGGHL EWRPATRLQT RTSKSSWTSD IDREINDNTK
     GCSSWTRFGR LSTVGRGEAV ELAHAGQHGQ PDAVAQPGRR LRWRLGQPLQ HQRVRVGGLR
     APGGPVGGAG RSQALRLGQQ GGPQLCRADC VRAIDSGRLS GRGIAGRQQR GCRISADIAG
     RCCCFSGTAR QSSGSGFQSA VGSRHGGFEV ARGHGGIKPL GLGDAPLLCR AAELLVHSGG
     GLLRRALPAA GRGIVAGGLG CVNDALRQEA DGVNRGRQDG DAAGAAVAGQ QHQAGGEGQA
     GVVTSCPLQA ARGHGAENRV VSADAGSVFH VLFFGVGHRV ELVGGGHQGA AEPDSVALLG
     VRENVHLDWG RLLAAERLHS LQAAVRCSLD VALQPFAEVF EHAGAAAQHD VLVQAAPVVD
     GAGLDHVVHG FGQRSLEVRV GKLRVEEDLG GQESLVADIH SERGIVDGVD ARVRLNPLGA
     LRVVLVELLR DVRAHVAVAL LDGLGGVHAH VRRDAHLAFA QQLLNEESDV AAGDGDMLNA
     AADDVAVGHR DDVGDTVAGV YDNPGEGSLA LRPGGPAGGQ GQHRLHSDVQ SRDVERLEHD
     LGGVLPVLRG VQWWLSQQEV VIFRLGAQVL EDGLLVEALH QVPVVHLAVP DRPLGGVAAG
     HRQRLVADVE IQIIQAGAEA PGLLGANFGS LLDADAAGHN ELRLAVASVA HLGVAGAVVN
     DNRWKPACHG CWSCGGRYLG GLQSVLKLGA HFTEKEWPGL LMNSYEAIQK TPVSRASSTG
     RTPAASSRRL RLAAARASAR QSASWRSQAA RRSRRRCSRL ARSSRPARAV SSASVIRAAK
     LSQSARSWRR LSASESRLAR RCAVSASTSC KAACSVGDDF SSGCSSWRSA FSTAIGSARR
     QRRRSSSQAA FCWPFEPGDG GRGSCWRGRC WRSCFWASSS SIRVSSWLRQ DRADSSRVWR
     SSTLAEEASR DAFSFRGEGS EAIQSRTTDL QLRLQQVRLR PCLRRRGTRV SHSLRFGVRS
     FDGSTPPRLR LSLTVVQSLA QFFNSEELRS ISLASWEPSS SNSCASRSPS SRSRSSVRSR
     SARRCWHSSW LSRQARSSSP ALWTAAPHST SAVSRRRFSV SSAAAPARTA ADSESPAAAL
     SRSSASLSEL TPAAATWASS SSSRCAPALT PAMESRSSRN LSSLTVSRRS LCSASCRYWL
     SWCTCSWLTV LAAAADAAAA ATASASASEP GGTNAEAAEL NEAESGRLSS LPSAWYRNTE
     AMTQPWDVAA KQSARRAFLV AFAKPLIVNN WPDSYHSRAW FRLSTLQSNM ALSMEGLDLA
     TDRPIFTASW PNGTRRSENG CDCGRDFKQT TGRSSSPLFN SSTTSKTLHS RIATSCCCCC
     CFCCCFCCLR LWLLLAPDTQ ADQRKQSAQN LEHTHTLPLH LATVTSTSTS GSMLMLVICL
     TVSAGDCRSI SRLCSRRRYR SHVFEPSPHG VLRVVRLSTF VGIRTGPFTG RFLSLAPLIR
     SAHTFSRLRT FFDVSVMRIR
//