ID A0A1I8GH72_9PLAT Unreviewed; 2131 AA.
AC A0A1I8GH72;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=SAM domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0001996-snap-gene-0.4-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0001996-snap-gene-0.4-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0001996-snap-gene-0.4-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-alpha subfamily.
CC {ECO:0000256|ARBA:ARBA00007026}.
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DR WBParaSite; maker-uti_cns_0001996-snap-gene-0.4-mRNA-1; maker-uti_cns_0001996-snap-gene-0.4-mRNA-1; maker-uti_cns_0001996-snap-gene-0.4.
DR Proteomes; UP000095280; Unplaced.
DR CDD; cd09562; SAM_liprin-alpha1_2_3_4_repeat1; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037620; Liprin-alpha_SAM_rpt_1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF20; LIPRIN-ALPHA, ISOFORM E; 1.
DR Pfam; PF00536; SAM_1; 2.
DR SMART; SM00454; SAM; 2.
DR SUPFAM; SSF47769; SAM/Pointed domain; 2.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054}.
FT DOMAIN 403..469
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 496..552
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 61..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 118..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 867..886
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 988..1032
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1172..1195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1590..1632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1819..1866
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..345
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1613..1632
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1831..1860
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2131 AA; 224301 MW; A9E48A35CD1E96DB CRC64;
AFDSTAVITS GAASTDSAYR QQQQQQQPQQ QQQDVHSLTL IIQQQLDAIN NEIRLIQEEK
ETTEQRAEEL ESRVGSGGSL HLQHQLSPTA SAAAAVPSSM ARSSAAATAA RSAAPGFAGQ
HYGMAHPATP QPVEPQRPHR PASAPYLAEY CDAAQPPTAR MPQSQQIWDR ASYYSQRCHY
RAGQQVGARA HSCATFRLRV CKKNPAMRLE FNSFIIFSIS SNKRCVWLGF LRSAHAITLL
LGWQLRSASS DRPSSSRAPL RRRLETSMLL GNCCYGNSKA RKAELKAASA ASPSLPAIQA
NSGGLQYFHS LPRGGGDWRD SPVSMGSINA PSPFDSSSTA SGRPYTLAGS RDGSIAGGSS
AASTVVAPSP HDFLGQKAED RRRRKKEELL EAVMRERTSF AQWSGPTVVA WLELWVGMPD
WYVAACRANV KSGAIMAALS DQEIQREIGI SNPLHRLKLR LAVQEMLAIT GPASGAGGAG
NPVSGQMGHD WVGNSWLPSL GLAQYRSAFM ECLVDARMLP RLGKKELRSH LRMTDGFHRD
SFACGVRALQ LLGFDRDALE ARRDACENSD TDLLVWSSDR VYRWLCRIGL PLSSDLSAAS
AGGQAVHQHP LQESGVHGAL MLLDESFDWS TLAQLLLLPQ NAGATPVRQL LEREFNQLVG
RERARHRQLL QAMQLQQQLR IPPHHLSERI SYGRGRVDAA WVAEGAARVP PAAVAAKGHR
AAGAGPAIVV PVHSGELTVI LKGQSVSRHG VVGAGIADAE AGVLGDEQVV SPAIVLTRLE
TVDTAAKDLT AATSGSKAGV AQDGEPNVIV YFVLASPTVK PEYSATYRIF DQVTASTLSS
FGALPPEVGA VSKAGLVLSP ASGKAQPSNQ SLLNHSAAAE KSAPQTADIR QSFVSDRKAE
AAHSQVGTAA HFVMQSTTLR LDDDVIEAAC TGAADVVENS AAEEFARDSF IRNERLFTSF
IDNCVHVRAE VHGVAGAGVA HGEAGVLSDV QDTRPGDGLD SQQLRGASGH LTGLPGAAAE
KSAPQTADSR QSFVSDRKAV AAHSQGGTAA HFVTHSTPLR PPDDVIAAAS TCAAADASCI
HTGLRGGAAV TEMELPAAPG TRTIHVIVPV LGGELHAFVI AERVAAHIGA ASQVRAEGHG
VAGAGIAHGE AGVLSHEEDI RPGDGLDSQQ LRGASGQLQS PPIDGSARCS GGEVGAPDRG
HQAELRLSSD GKGCAVAGLK CGALCGALEA TLFGSLCAAS QSEPAWTLAR GKFQVYPAPR
AQLVFQVYRL TLLDPYWSKL SQVVSGGQSD RPLRTSGHPS SALGYRPRGF FSLSAWDSAW
YLVISLGLAS GGLGIDPRLD FLSIVAGEIL RPHLSCERML DLALRASSSR SSSSRRLGFK
LGRMVSRELS YSGESRPRPR LQPMSCDCRG SRKRLRRRPF RRRMLRRHFE LDGWGAGCWL
GRLSTIGLLL LLLLLLLLSS PPAAAGQRRG PGKAGGQQSQ LHHVVPDKAP ALRQQLQTQQ
VAALGAEALQ RGEAPGQIRI LAQVGAEQVQ AGLADGQHAG LELKLLRLLR RLVLPLGFSQ
LVLRMMRRVL EAGQMLGSND RDFIRVHLSS MEGPRQDAQD RRRGLAASLA ARMPQSSRAS
AGSSGRRPSN TSVMHWCASS ADSTWSVRLN KRANKNSLLT DEPQLLLVLV LVLMVVMVRG
RGSRAELGVL LPLEQHVANV VAGVGVPLHD AVLLEQGPAD RAGPAKGTLA SSAVSASSPM
RVKLQLPMVA VQQVDGHGGR AAPEYRQRQQ LASGGRKSAP GALLLPLGGA LQAAQAKLRV
AALIGEGVQS CPVQVAAQER SEWASSSEPE SAPPPTIPMP PTPDPPPPPP PPPPLLPPVP
TQSGQQALLQ QSLGGAQHHG IFQRVGGFDQ LHGGGEFAGG GELLRVRVQQ QRLLLAAASA
SARGAAVTAA SAANTDAADE AAAAAGASPI AGPKIGRIGA ASCRLVLLLL LLLLLLLLGL
AGENAQSGAQ QRVLRLGWLG QQAGGHQLAS AAVRLLGQAM PVGLSGGHSL EQQLVGLAQD
AAGAGRAGSS LLLLLVAWQR SGRSVAGRVG GVISAVVVFV AADTVDAVAA VGVGVDAAVT
AATPPPPLAM RPWVNGGARL GVRSQSCELA C
//
