ID   A0A1I8GJT3_9PLAT        Unreviewed;       193 AA.
AC   A0A1I8GJT3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=MARVEL domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0002170-snap-gene-0.43-mRNA-1};
GN   ORFNames=BOX15_Mlig017797g2 {ECO:0000313|EMBL:PAA91508.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0002170-snap-gene-0.43-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0002170-snap-gene-0.43-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:PAA91508.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA91508.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA91508.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; NIVC01000085; PAA91508.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I8GJT3; -.
DR   STRING; 282301.A0A1I8GJT3; -.
DR   WBParaSite; maker-uti_cns_0002170-snap-gene-0.43-mRNA-1; maker-uti_cns_0002170-snap-gene-0.43-mRNA-1; maker-uti_cns_0002170-snap-gene-0.43.
DR   Proteomes; UP000095280; Unplaced.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008253; Marvel.
DR   PANTHER; PTHR22776; MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR22776:SF49; RE01453P; 1.
DR   PROSITE; PS51225; MARVEL; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW   ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        34..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        64..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        124..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          29..154
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000259|PROSITE:PS51225"
SQ   SEQUENCE   193 AA;  20421 MW;  53A4E288F769C1F1 CRC64;
     METDAYKATT TETTATHSEG PGVGLDKDFV RTPLGIVLIA AFVSAVILFI CGTVFPWSAH
     GGGFVAFVGT TAAFGTGILF VLYLIRLLPK IPGPFGLVIL IYLAVVVILS LIAFILSAVN
     GKGIGGAAIA SAVFAVPTLG LHGYFGFLMF RKYQVLKNHF HKGECGHSYS VTTTQQNYEA
     SHPEDAAPAY GNY
//