ID   A0A1I8GK63_9PLAT        Unreviewed;       418 AA.
AC   A0A1I8GK63;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   22-FEB-2023, entry version 18.
DE   SubName: Full=Alpha-carbonic anhydrase domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0002220-snap-gene-0.9-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0002220-snap-gene-0.9-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0002220-snap-gene-0.9-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC       {ECO:0000256|ARBA:ARBA00010718}.
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DR   AlphaFoldDB; A0A1I8GK63; -.
DR   WBParaSite; maker-uti_cns_0002220-snap-gene-0.9-mRNA-1; maker-uti_cns_0002220-snap-gene-0.9-mRNA-1; maker-uti_cns_0002220-snap-gene-0.9.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR   InterPro; IPR001148; CA_dom.
DR   InterPro; IPR036398; CA_dom_sf.
DR   InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR   PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR   PANTHER; PTHR18952:SF138; CARBONIC ANHYDRASE-RELATED PROTEIN 10; 1.
DR   Pfam; PF00194; Carb_anhydrase; 1.
DR   SMART; SM01057; Carb_anhydrase; 1.
DR   SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR   PROSITE; PS51144; ALPHA_CA_2; 1.
PE   3: Inferred from homology;
FT   DOMAIN          111..372
FT                   /note="Alpha-carbonic anhydrase"
FT                   /evidence="ECO:0000259|PROSITE:PS51144"
SQ   SEQUENCE   418 AA;  46601 MW;  A09FCECBEF23BCEA CRC64;
     NKAESIPGPP GPPLIGWAAC LPIICAAYIH NAIPSASSPA ITLRGLTAAL LLGATGQGRQ
     TDRQPRMPLG YPAGAVRSFN GGWATLLLLM ATLPAALSVW KDKNWNDQLD DWWHYRTGII
     GGPEQWGRKA YMTYNLWQIC HRGRHQSPIN ISTANLVYDS NLGPLTLTGA DEAISLSVRN
     TGHDIEIRLG SERLVLSQGP LSYSYTIFGA LIKFGSRSDR GSDHWIDSRA FPGELQFYGY
     NSDLYENYTM ALNSAHGIVA LSAFMQFGDV TTVDMNPDGY QANYQRTEIH GIKVRSLLPE
     TSEYITYEGS LPFPGCHESV TWIILNLPVT VRTEELSILR SLRISSVQTS AYMADNFRPT
     QLLHQRTVRT NIRLRNRLKD EPRCQSLESV RSQEVRSLKK ICSGLSDLHQ LTKTFLEY
//