ID A0A1I8GK64_9PLAT Unreviewed; 169 AA.
AC A0A1I8GK64;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Calcineurin subunit B type 1 {ECO:0000313|WBParaSite:maker-uti_cns_0002291-snap-gene-0.3-mRNA-1, ECO:0000313|WBParaSite:maker-uti_cns_0014022-snap-gene-0.3-mRNA-1};
GN ORFNames=BOX15_Mlig010667g3 {ECO:0000313|EMBL:PAA83193.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0002291-snap-gene-0.3-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0002291-snap-gene-0.3-mRNA-1, ECO:0000313|WBParaSite:maker-uti_cns_0014022-snap-gene-0.3-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:PAA83193.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA83193.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA83193.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the calcineurin regulatory subunit family.
CC {ECO:0000256|ARBA:ARBA00023774}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NIVC01000429; PAA83193.1; -; Genomic_DNA.
DR STRING; 282301.A0A1I8GK64; -.
DR WBParaSite; maker-uti_cns_0002291-snap-gene-0.3-mRNA-1; maker-uti_cns_0002291-snap-gene-0.3-mRNA-1; maker-uti_cns_0002291-snap-gene-0.3.
DR WBParaSite; maker-uti_cns_0014022-snap-gene-0.3-mRNA-1; maker-uti_cns_0014022-snap-gene-0.3-mRNA-1; maker-uti_cns_0014022-snap-gene-0.3.
DR Proteomes; UP000095280; Unplaced.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008597; F:calcium-dependent protein serine/threonine phosphatase regulator activity; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR015757; Calcineur_B.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR45942; PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1; 1.
DR PANTHER; PTHR45942:SF1; PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1; 1.
DR Pfam; PF13499; EF-hand_7; 2.
DR PRINTS; PR01697; PARVALBUMIN.
DR SMART; SM00054; EFh; 4.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 3.
DR PROSITE; PS50222; EF_HAND_2; 4.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 17..45
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 49..84
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 86..121
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 127..162
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 169 AA; 19313 MW; B2761F2D9CE274E8 CRC64;
MGNEVSLPEL CAHFDTEEIR RLGKRFKKID LDGSGALSVD EFLRLPELQQ NPLVQRVIDI
FDTDQNGEVD FKEFIEGMSQ FSVRGDKDSK LRFAFRIYDM DKDGYISNGE LFQVLKMMVG
SNLKDAQLQQ IVDKTIIFAD KDGDGRISFS EFCDLVGTMD VHKKMTIDI
//
