ID   A0A1I8GRY6_9PLAT        Unreviewed;       986 AA.
AC   A0A1I8GRY6;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=N-acetyltransferase domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0002944-snap-gene-0.5-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0002944-snap-gene-0.5-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0002944-snap-gene-0.5-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=L-ascorbate; Xref=ChEBI:CHEBI:38290;
CC         Evidence={ECO:0000256|ARBA:ARBA00001961};
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DR   AlphaFoldDB; A0A1I8GRY6; -.
DR   WBParaSite; maker-uti_cns_0002944-snap-gene-0.5-mRNA-1; maker-uti_cns_0002944-snap-gene-0.5-mRNA-1; maker-uti_cns_0002944-snap-gene-0.5.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:InterPro.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   CDD; cd04301; NAT_SF; 1.
DR   Gene3D; 3.40.630.30; -; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   Gene3D; 2.60.120.620; q2cbj1_9rhob like domain; 1.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR006984; Fcf1/Utp23.
DR   InterPro; IPR000182; GNAT_dom.
DR   InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR   InterPro; IPR006620; Pro_4_hyd_alph.
DR   InterPro; IPR044862; Pro_4_hyd_alph_FE2OG_OXY.
DR   InterPro; IPR007146; Sas10/Utp3/C1D.
DR   PANTHER; PTHR12416:SF3; RRNA-PROCESSING PROTEIN UTP23 HOMOLOG; 1.
DR   PANTHER; PTHR12416; UNCHARACTERIZED; 1.
DR   Pfam; PF13640; 2OG-FeII_Oxy_3; 1.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   Pfam; PF04900; Fcf1; 1.
DR   Pfam; PF04000; Sas10_Utp3; 1.
DR   SMART; SM00702; P4Hc; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   PROSITE; PS51471; FE2OG_OXY; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          578..705
FT                   /note="Fe2OG dioxygenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51471"
FT   DOMAIN          840..976
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
FT   REGION          205..236
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          714..741
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        205..220
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   986 AA;  111223 MW;  26DDB6C011C3180E CRC64;
     MRAKKLKRNR RILDACAETF GLADPLPVLI DSSFARMALR HKVNMSDQLH RLLDGRNLAL
     CTTRCVIKEC QLLGPVMAGT LKVLSCLELH PCHHKRATTA VRCLTKALRP VATEPTVDEA
     SSVSASDPNW RPLLASNSER LRSLAHELTG MPCLLLEHGQ PLLTGLPADT RRLLAERRLR
     GLRAEADEAA AVAAAATVDA SVLKRRRRRQ RGANPLSCLK KKRKRQTEQQ QQKSDEVHCN
     IDNNVDLSST ICRRRKRGRR AGWSRRPWHV RQFIVEQLQQ QFLVFITATS PMEVDDDLEA
     DSGGVGGSQL DDIPDEIRAN LLRLVGSVDE VESAFDAVMR QPYEERTADM TPLEKAKFDL
     TFLYGMNALY WVYLRCQGQD PSKHSVRSEL DRVVGPMRRV QAEADKARQP RIDVDAAKRF
     VKAGMWRAAH DKARQRRLER EQAAATAADE KAIGDENEEA NLDPDESVEA AGICRVPISD
     FGNQGFVLRG FLSPGECQRL VDSAEASGGL KPTPFFRQEY RSCHRLVLHE PELARQMFLR
     LRPYLPDKLT FNGQDDPITS HRVHGAPWLL KGNWEPYCLN PVLRLCRYHP GQHFSPHYDG
     LLVHDDACRS MQTFMVYLTD NPASDGGATN FLDDGLSMSS LISTTESATE SDGTERQRMS
     APQSQIICQV HPERGSLLVF NHYRLHEGER LAAGVKYILR SDIMYRRITA APQSDEKFRE
     ALRLQQEAER LESRGQADEA QLISGSMEDQ AKEEQLVCRT GLKLRMRLLT AKEAEEYFWV
     ALMPYSWTNR RLAEIIATCW QTRTACATLA ALAAWRWRRP VAWLLAGALA PTALLHSLRL
     LLWLISTRQL PDYARFPEFW CGEGPNRLYG VFLDSAEAGQ QQPPLVGTVA SLHLDGDTCE
     LQRLGVLPAY RGHGVGDAVC RRLMRLCANR GYRRMQLGTT QLQQYAVDIY ERLGFIRTDQ
     FTSIILPGVP IYRYEAELSD AAGPLD
//