ID A0A1I8GTQ9_9PLAT Unreviewed; 683 AA.
AC A0A1I8GTQ9;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=ATPase_AAA_core domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0003112-snap-gene-0.5-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0003112-snap-gene-0.5-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0003112-snap-gene-0.5-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the dynein heavy chain family.
CC {ECO:0000256|ARBA:ARBA00008887}.
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DR AlphaFoldDB; A0A1I8GTQ9; -.
DR WBParaSite; maker-uti_cns_0003112-snap-gene-0.5-mRNA-1; maker-uti_cns_0003112-snap-gene-0.5-mRNA-1; maker-uti_cns_0003112-snap-gene-0.5.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd00890; Prefoldin; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF1; DYNEIN HEAVY CHAIN; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12777; MT; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 229..353
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 447..648
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 442..486
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 625..680
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 683 AA; 72829 MW; A8B1103B1F87CC76 CRC64;
AASRRGSTSS LTSGGVSGVG RSGRRGVAQS PFFGPLFDND SAATLEEPEA GVAGSANNTE
AAASRRELFD LTGQLFVRFG VLAAGSPSPP GGGAAANVYT ECNSSELSAA AASAVSTASG
SRRHRQKAAS RSKGERDEHD SDVTAAVDPD LVLLESGLRH LARLTRCLAL PTGGHAILAS
ATPGVGRSTL TRLAARMSLA QTQPVCLLIS SAALAASGGS DAIDVVVATM RDGACPGLFD
VATDSSSEAK SKATAAASTQ PAFQLAVRSN LRCVLSLNWR DSKLGSLHSV LSRHPELLHA
CQCIDWYSDW SQDTYAAVAR HWLESGAFDL SLTTATSAKT ESIVAATAQA AAAAHVTAGR
MLSGLYAGLS PESPMLPTQA TPLAFKEFLS LATGLAGDLR RAAIRDIEAG SSLADSISAE
QATLDAQKLE AEAARPKLEA QLWDVEMQAQ AIQQQREKYK AQLDACREQE AKVKQLLEPL
EKMKKESQDS GQAKLDPVYE AAIRAAESLQ PQHLEEVRSY REPPEPVKAV MSVICMLFDT
ETESWEAAKE LMMKEDLQEL LLYYDKASMP DSKFKRLTAA LSRPEMSEMA VSSASKAAAK
VRDWLEAVQQ FTAVSRDLNP AIGALRAAEE RVSREQTRLG RMRVEAQKQL ESLNAAIGLH
REASLAARQL RQRIARMQVK LLD
//
