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Database: UniProt
Entry: A0A1I8GTX8_9PLAT
LinkDB: A0A1I8GTX8_9PLAT
Original site: A0A1I8GTX8_9PLAT 
ID   A0A1I8GTX8_9PLAT        Unreviewed;      1497 AA.
AC   A0A1I8GTX8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   28-FEB-2018, entry version 8.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|WBParaSite:maker-uti_cns_0003091-snap-gene-0.8-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Platyhelminthes; Rhabditophora; Macrostomorpha;
OC   Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0003091-snap-gene-0.8-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0003091-snap-gene-0.8-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=26392545; DOI=10.1073/pnas.1516718112;
RA   Wasik K., Gurtowski J., Zhou X., Ramos O.M., Delas M.J.,
RA   Battistoni G., El Demerdash O., Falciatori I., Vizoso D.B.,
RA   Smith A.D., Ladurner P., Scharer L., McCombie W.R., Hannon G.J.,
RA   Schatz M.;
RT   "Genome and transcriptome of the regeneration-competent flatworm,
RT   Macrostomum lignano.";
RL   Proc. Natl. Acad. Sci. U.S.A. 112:12462-12467(2015).
RN   [2] {ECO:0000313|WBParaSite:maker-uti_cns_0003091-snap-gene-0.8-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   WBParaSite; maker-uti_cns_0003091-snap-gene-0.8-mRNA-1; maker-uti_cns_0003091-snap-gene-0.8-mRNA-1; maker-uti_cns_0003091-snap-gene-0.8.
DR   Proteomes; UP000095280; Genome assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   Pfam; PF02026; RyR; 2.
DR   Pfam; PF00622; SPRY; 2.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 3.
DR   SMART; SM00449; SPRY; 2.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 2.
DR   PROSITE; PS50919; MIR; 4.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000095280};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095280};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN      138    192       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      252    306       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      312    370       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      377    435       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      627    840       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1055   1257       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
SQ   SEQUENCE   1497 AA;  165941 MW;  3B55981EAF5A656F CRC64;
     SLLLVAAAAA AVHPTSHSSC RQKRPPGTLQ ATSLLLALGD RSSQGMEGES DEDTSFLRTD
     DLLSLSCVIH NASGNSQRVS LAAQGFGNRM CYLENLSNKD VPPDFSVCKF VLEKALSVRA
     LQEMVSSKSN VDSGQSGHKT LLYGHAILLR HHASSMYLTC LTTSSSRDKL AFDVGLEEQP
     QGESCWWTVH PASKTRSDGE KVRIGDDFIL VSVSSERYLH FSPEDNGVLA SFRQTLWTII
     PVSSGAIRQK NLSCVFGGDV LRFTHGDECL TICQEESEAP TDLPKVMYET GDAKSQARSL
     WRVEHVKIRW TGGLFSWSCK VRIRHVTSGR YLGVTDSNLL TTVPVEQASE EVTAFCLMQT
     KDDKMSKEER EEEGMGAADV KYDDTYSFLQ HIASGLWLSY KTYETKKRGI GRVEEKQAVL
     LVEGHMDDAF TFAKSQDEDS KSAVAIRRCA AFFHNLLKAL DGLLAEGVQS AAWQATNIDE
     VQRSLKDLID FFEFPDESEE HEMRVMKLKG LKNRQGLFQE EGMISLVLDT IDKFSSTFKS
     SRDFAAICGE DRSGCYNTIS NYLYLLLAAL IRGNRPNCAQ FAQTQRLNWL FSRLEGQEAA
     QGVLDVLFSV LTHSPEALNM IRENHIQTIV GLLDRQGRDS KILEVLCSLC VSGSQGAVRL
     NQNLISNTLL PDRDLLLQTR LVDHVRCFRP NVSVKIADGV AMYSRWCFEV VVDSIEQKTD
     NPTHLRIGWA NADGFLPYPA RGTNWGCNGL GDDIYSFAFD GNHLWTNQSS QPVQPVPLQL
     KKGDVIGSAI DLSIPRITFS VNGQTVRGFF KDFDKWGTFY PCVSLGAKVS VRFLFGGSHG
     RLKFGPLDTF SPISDAILPG RKLRIEPCFN FGFIEKSIYQ GPIDVGPYNN FKPSPIDCAA
     MQAPAAVDQI RERLAENLHE IWAMKKIEQG WTFGEQRSDE YKTNPCLTTF SQLPDYERTY
     NLSLAQETLK VIFILGYNIV PDPQKETRVK TVKLGNSFVQ PNGYKPMPID LSQYALSPAL
     EELADYLAEN THNLWGRDRI AQGWTWGIEE DPVLKRSPFL VPFKHVDPAI QAVNRASSSE
     IIRTILAFGY DIERSSSSDV REELIMQRML EPCHSDISRT YRVETTWAVS QGKWYFEFEV
     MSEGNIRVGF MQADSRAGVL VGDSIGSYAF DCCSARKWHV ESDRFGKRCH QGDVVGCLID
     LDDGTIYFSL NGELMMDSVG QEIAFKGIQV NAKTGYVPAF SLGVGQSAKL NLGQDVKSFK
     YFTCCGLQEG FEPFCQHALG AADVVRPPGD ELRDHLGGEL ALAHPCPALG RRHPLISIST
     KYVPSAQEDH LEVVRLSLPV RCHQQFTSRS LAQRRAEVDN FRKKLDPRLQ QRGGGEGGGP
     TSLMVPKGAA DGQHLPSTTA AAAAATGGAK KKTKIANFFK KQKSHGGADD VSQSAVTAIL
     TPDASADAGL FGKFGGEDTD HLQYEMQVRG WAAHSQTVTF PNCRIPSCHI PKLSHSQ
//
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