ID   A0A1I8GWR8_9PLAT        Unreviewed;       298 AA.
AC   A0A1I8GWR8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=RING-type domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0003478-snap-gene-0.8-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0003478-snap-gene-0.8-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0003478-snap-gene-0.8-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SH3RF family.
CC       {ECO:0000256|ARBA:ARBA00008649}.
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DR   AlphaFoldDB; A0A1I8GWR8; -.
DR   WBParaSite; maker-uti_cns_0003478-snap-gene-0.8-mRNA-1; maker-uti_cns_0003478-snap-gene-0.8-mRNA-1; maker-uti_cns_0003478-snap-gene-0.8.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR018957; Znf_C3HC4_RING-type.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   Pfam; PF07653; SH3_2; 1.
DR   Pfam; PF00097; zf-C3HC4; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS50002; SH3; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}; Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          54..108
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          173..251
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          140..160
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..37
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        141..160
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   298 AA;  32762 MW;  0207316A43D59B31 CRC64;
     MMQVPPVPRR NRRNRSRSNA NNSNETQQKQ QESEQPKAYH FNQCRNIIKS AIKCPICFES
     MLDPSADSRV LPCQHAFCRS CLAKLLDSCT SSAGDSTRIG GPVCPECRAP ISAIRADDLP
     PNVQLNRLCN ELDELQQKHH SSLDSSASKS SGDSANSNCR RRQQRQSCTL TVLSGDFCTA
     TREFNYRSTD SRYLELRPGD LIEIISRRCS TALDAPSDAA ASTASAPGWA YGRIGQRKGY
     FPLACTRPVV GNQRKVSANQ SSKKCDAYPV VCALYDYQPS DAISLDCANQ STAVSLLP
//