ID   A0A1I8H0G1_9PLAT        Unreviewed;       424 AA.
AC   A0A1I8H0G1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=PBPe domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0003888-snap-gene-0.1-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0003888-snap-gene-0.1-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0003888-snap-gene-0.1-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A1I8H0G1; -.
DR   WBParaSite; maker-uti_cns_0003888-snap-gene-0.1-mRNA-1; maker-uti_cns_0003888-snap-gene-0.1-mRNA-1; maker-uti_cns_0003888-snap-gene-0.1.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR   InterPro; IPR019594; Glu/Gly-bd.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   PANTHER; PTHR18966:SF422; KAINATE-TYPE IONOTROPIC GLUTAMATE RECEPTOR SUBUNIT 1D; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR   SMART; SM00079; PBPe; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        229..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        302..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          106..424
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00079"
SQ   SEQUENCE   424 AA;  47402 MW;  EBAD586DE4022749 CRC64;
     LNSSLYESSL AHHLLSGINA SNVAMTQLSL PDTDATGFSQ LAASDLGMIE KVVQKPSVNF
     SFTLSHLYAD SIVPFANWSL GEGFRQLPNA STLHRSIQQA FVSSQNLSVA TKIYPPFVMY
     RTEDNDGKPT VWQRSLLSGL KYTIHHVFDN HFGSIVNSSG NIEQWNGLVY ELMNNMADVA
     VGPITVTYER ERVIDFTAPY MSFGLAVIMK QSEDKPALFQ FLNPFHRDVW LFTLLAVAGT
     ALFIFAARLS PYEWLPPSDS SEAAAENSWT LHNAVWFSVS SLLQQGCETS PSAASVRIAG
     TFWWFFILVF ISSYTANLAA FLTVSKLNEI SNLQQLASQD RVKYGMEPSG STFSFFLSTP
     DATYQKMHQQ MEVALSECVG GDFAYITESP LSLYYRGARP RLQPRRAGRC FQSRHLRFAL
     WFKA
//